SCHEMBL1685684

SCHEMBL1685684

CC(C)C1COC(C(C)(C)C2=NC(C(C)C)CO2)=N1

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.43
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
MAPT P10636 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22661725 1.00 NPC1 (0.43) NPC1MEN1KMT2AMAPTRAB9A
SCHEMBL918791 1.00 NPC1 (0.43) NPC1MEN1KMT2AMAPTRAB9A
SCHEMBL29549533 1.00 NPC1 (0.43) NPC1MEN1KMT2AMAPTRAB9A
SCHEMBL918568 1.00 NPC1 (0.43) NPC1MEN1KMT2AMAPTRAB9A
SCHEMBL30403231 0.98 NPC1 (0.42) NPC1MEN1KMT2AMAPTRAB9A
SCHEMBL29001613 0.98 NPC1 (0.42) NPC1MEN1KMT2AMAPTRAB9A
SCHEMBL19765232 0.88 NPC1 (0.43) NPC1MEN1KMT2AMAPTRAB9A
SCHEMBL27932371 0.88 NPC1 (0.43) NPC1MEN1KMT2AMAPTRAB9A
SCHEMBL12116904 0.80 NPC1 (0.38) NPC1MEN1KMT2AMAPTRAB9A
SCHEMBL20500207 0.79 NPC1 (0.40) NPC1MEN1KMT2AMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113004517-B Modified epoxy resin, adhesive, preparation method and application thereof 广州市白云化工实业有限公司 2022-08-09 CN claimed
CN-111548329-B Preparation method of brivaracetam 浙江乐普药业股份有限公司 2022-06-17 CN claimed
US-20250155812-A1 PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE RESIN FILM, PHOTOSENSITIVE DRY FILM, AND PATTERN-FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-05-15 US disclosed
CN-114391030-B Chemically compatible fluoropolymer blends 大金美国股份有限公司 2024-04-19 CN disclosed
CN-115304568-B Asymmetric synthesis method of 6-azidomethylene-1-aryl-3-oxabicyclo [3,1,0] hex-2-one 扬州大学 2024-03-26 CN disclosed
CN-116102527-B Preparation method of peach aldehyde 万华化学集团股份有限公司 2023-12-19 CN disclosed
CN-116102527-A Preparation method of peach aldehyde 万华化学集团股份有限公司 2023-05-12 CN disclosed
CN-116057105-A Fluoropolymer and liquid crystal polymer blends 大金美国股份有限公司 2023-05-02 CN disclosed
CN-113004517-B Modified epoxy resin, adhesive, preparation method and application thereof 广州市白云化工实业有限公司 2022-08-09 CN disclosed
CN-111548329-B Preparation method of brivaracetam 浙江乐普药业股份有限公司 2022-06-17 CN disclosed
CN-114031573-B Method for recovering ligand in S- (+) -2, 2-dimethyl cyclopropane formic acid asymmetric synthesis 深圳市海滨制药有限公司 2022-04-29 CN disclosed
CN-114391030-A Chemically compatible fluoropolymer blends 大金美国股份有限公司 2022-04-22 CN disclosed
CN-113692401-A Process for producing aromatic amino acid derivative 中外制药株式会社 2021-11-23 CN disclosed
EP-3122707-A1 METHOD FOR COUPLING A FIRST AROMATIC COMPOUND TO A SECOND AROMATIC COMPOUND Dow Global Technologies LLC (US) 2017-02-01 EP disclosed
WO-2015148931-A1 METHOD FOR COUPLING A FIRST AROMATIC COMPOUND TO A SECOND AROMATIC COMPOUND DOW GLOBAL TECHNOLOGIES LLC (US) 2015-10-01 WO disclosed
EP-1950208-B1 PROCESS FOR PRODUCING 6,6-DIMETHYL-3-OXABICYCLO[3.1.0]HEXAN-2-ONE SUMITOMO CHEMICAL CO (JP) 2012-05-02 EP disclosed
US-7928253-B2 Method of producing 6,6-dimethyl-3-oxabicyclo[3.1.0]hexan-2-one SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-04-19 US disclosed
US-20100168463-A1 METHOD OF PRODUCING 6,6-DIMETHYL-3-OXABICYCLO[3.1.0]HEXAN-2-ONE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-07-01 US disclosed
EP-1950208-A1 PROCESS FOR PRODUCING 6,6-DIMETHYL-3-OXABICYCLO[3.1.0]HEXAN-2-ONE Sumitomo Chemical Company, Limited (JP) 2008-07-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100168463-A1 METHOD OF PRODUCING 6,6-DIMETHYL-3-OXABICYCLO[3.1.0]HEXAN-2-ONE CYP1B1, HACL2, CMA1 NPC1 2056/4885MEN1 3183/4885KMT2A 3339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.