Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 19/20 | 0.47 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16857870 | 0.93 | EGLN1 (0.51) | EGLN1EGLN3 | |
| SCHEMBL16857776 | 0.91 | EGLN1 (0.46) | EGLN1EGLN3 | |
| SCHEMBL16857891 | 0.91 | EGLN1 (0.49) | EGLN1MGLL | |
| SCHEMBL16857919 | 0.89 | EGLN1 (0.48) | EGLN1EGLN3 | |
| SCHEMBL16857819 | 0.89 | EGLN1 (0.48) | EGLN1MGLL | |
| SCHEMBL3020636 | 0.86 | EGLN1 (0.59) | EGLN1EGLN3 | |
| SCHEMBL16857920 | 0.86 | EGLN1 (0.52) | EGLN1 | |
| SCHEMBL16857897 | 0.84 | EGLN1 (0.51) | EGLN1EGLN3 | |
| SCHEMBL16857773 | 0.84 | EGLN1 (0.56) | EGLN1MGLL | |
| SCHEMBL16857786 | 0.84 | EGLN1 (0.57) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396316-B1 | QUINAZOLINONES AS PROLYL HYDROXYLASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2015-07-01 | — | — | EP | claimed |