SCHEMBL16857760

SCHEMBL16857760

O=C(O)Oc1cnn(-c2nc3ccc(Oc4cccc(Cl)c4Cl)cc3c(=O)[nH]2)c1

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 19/20 0.44
MGLL Q99685 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16857904 0.90 EGLN1 (0.44) EGLN1MGLL
SCHEMBL3029912 0.88 EGLN1 (0.58) EGLN1
SCHEMBL16857878 0.87 EGLN1 (0.45) EGLN1MGLL
SCHEMBL16857864 0.86 EGLN1 (0.50) EGLN1MGLL
SCHEMBL16857911 0.86 EGLN1 (0.50) EGLN1MGLL
SCHEMBL16857754 0.86 EGLN1 (0.44) EGLN1MGLL
SCHEMBL16857749 0.85 EGLN1 (0.45) EGLN1
SCHEMBL16857784 0.85 EGLN1 (0.54) EGLN1MGLL
SCHEMBL16857798 0.85 EGLN1 (0.49) EGLN1
SCHEMBL16857775 0.85 EGLN1 (0.49) EGLN1MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2396316-B1 QUINAZOLINONES AS PROLYL HYDROXYLASE INHIBITORS JANSSEN PHARMACEUTICA NV (BE) 2015-07-01 EP claimed