Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16859954 | 0.92 | ALK (1.00) | ALKPDPK1 | |
| SCHEMBL15562455 | 0.89 | ALK (0.81) | ALKPDPK1 | |
| SCHEMBL15562327 | 0.88 | ALK (0.78) | ALKPDPK1 | |
| Hydrochloric Acid SCHEMBL15562388 | 0.86 | ALK (0.75) | ALKPDPK1 | |
| SCHEMBL15557197 | 0.86 | ALK (0.75) | ALK | |
| SCHEMBL16870820 | 0.85 | ALK (0.74) | ALK | |
| SCHEMBL15556776 | 0.85 | ALK (0.74) | ALKPDPK1 | |
| SCHEMBL17282561 | 0.85 | ALK (0.74) | ALK | |
| SCHEMBL15599427 | 0.84 | ALK (0.73) | ALK | |
| SCHEMBL16867140 | 0.84 | ALK (1.00) | ALKPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150183781-A1 | 5-(1H-Pyrazol-4-yl)-1H-Pyrrolo[2,3-b]Pyridine Derivatives as Kinase Inhibitors | Um Pharmauji Sdn. Bhd. (MY) | 2015-07-02 | — | — | US | claimed |
| US-20150183781-A1 | 5-(1H-Pyrazol-4-yl)-1H-Pyrrolo[2,3-b]Pyridine Derivatives as Kinase Inhibitors | Um Pharmauji Sdn. Bhd. (MY) | 2015-07-02 | — | — | US | disclosed |
| US-20150183781-A1 | 5-(1H-Pyrazol-4-yl)-1H-Pyrrolo[2,3-b]Pyridine Derivatives as Kinase Inhibitors | Um Pharmauji Sdn. Bhd. (MY) | 2015-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150183781-A1 | 5-(1H-Pyrazol-4-yl)-1H-Pyrrolo[2,3-b]Pyridine Derivatives as Kinase Inhibitors | MAP3K1, MAP3K5, MAP3K3 | ALK 438/4885PDPK1 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.