Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 15/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.37 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.37 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.36 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3762010 | 0.93 | LRRK2 (0.60) | LRRK2ALDH1A1HTT | |
| SCHEMBL3775929 | 0.93 | LRRK2 (0.60) | LRRK2ALDH1A1HTT | |
| SCHEMBL3775098 | 0.91 | LRRK2 (0.57) | LRRK2ALDH1A1HTT | |
| SCHEMBL3773105 | 0.90 | LRRK2 (0.56) | LRRK2ALDH1A1 | |
| SCHEMBL10224703 | 0.90 | LRRK2 (0.71) | LRRK2ALDH1A1 | |
| SCHEMBL3768652 | 0.90 | LRRK2 (0.56) | LRRK2ALDH1A1 | |
| SCHEMBL462960 | 0.88 | LRRK2 (0.55) | LRRK2ALDH1A1HTT | |
| SCHEMBL3778615 | 0.87 | LRRK2 (0.54) | LRRK2ALDH1A1 | |
| SCHEMBL3775692 | 0.87 | LRRK2 (0.54) | LRRK2ALDH1A1 | |
| SCHEMBL3766638 | 0.87 | LRRK2 (0.53) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408772-B1 | COMPOUNDS | MEDICAL RES COUNCIL TECHNOLOGY (GB) | 2015-07-01 | — | — | EP | disclosed |