Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 11/20 | 0.88 |
| ▸ | MAPT | P10636 | 8/20 | 0.88 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.88 |
| ▸ | TP53 | P04637 | 4/20 | 0.88 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.88 |
| ▸ | TSHR | P16473 | 3/20 | 0.88 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.88 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.88 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.88 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | USP2 | O75604 | 4/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.67 |
| ▸ | ODC1 | P11926 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | GALR3 | O60755 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12315590 | 0.96 | CYP3A4 (0.88) | CYP3A4MAPTSMN1; SMN2TP53CYP2C19 | |
| Deguelin SCHEMBL29405854 | 0.94 | CYP3A4 (1.00) | CYP3A4MAPTSMN1; SMN2TP53CYP2C19 | |
| Deguelin SCHEMBL3365130 | 0.94 | CYP3A4 (1.00) | CYP3A4MAPTSMN1; SMN2TP53CYP2C19 | |
| Deguelin SCHEMBL30910172 | 0.94 | CYP3A4 (1.00) | CYP3A4MAPTSMN1; SMN2TP53CYP2C19 | |
| Deguelin SCHEMBL19365775 | 0.94 | CYP3A4 (1.00) | CYP3A4MAPTSMN1; SMN2TP53CYP2C19 | |
| Deguelin SCHEMBL73183 | 0.94 | CYP3A4 (1.00) | CYP3A4MAPTSMN1; SMN2TP53CYP2C19 | |
| SCHEMBL14134482 | 0.91 | CYP3A4 (0.77) | CYP3A4MAPTSMN1; SMN2TP53CYP2C19 | |
| SCHEMBL16694452 | 0.90 | CYP3A4 (0.86) | CYP3A4MAPTSMN1; SMN2TP53CYP2C19 | |
| SCHEMBL19365481 | 0.90 | CYP3A4 (0.86) | CYP3A4MAPTSMN1; SMN2TP53CYP2C19 | |
| SCHEMBL11946418 | 0.88 | CYP3A4 (0.86) | CYP3A4MAPTSMN1; SMN2TP53CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9745280-B2 | Compound or pharmaceutically acceptable salt thereof, and pharmaceutical composition containing same as active ingredient | SNU R&DB FOUNDATION (KR) | 2017-08-29 | — | — | US | disclosed |
| US-20160340331-A1 | NOVEL COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | SNU R&DB FOUNDATION (KR) | 2016-11-24 | — | — | US | disclosed |
| US-20150183797-A1 | NOVEL COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | SNU R&DB FOUNDATION (KR) | 2015-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150183797-A1 | NOVEL COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | HSP90AB1, HSP90AA1, HIF1AN | CYP3A4 4301/4885MAPT 1940/4885SMN1; SMN2 2785/4885 |
| US-20160340331-A1 | NOVEL COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | HSP90AB1, HSP90AA1, HSP90AB2P | CYP3A4 4358/4885MAPT 1864/4885SMN1; SMN2 2039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.