Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TARDBP | Q13148 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4252809 | 0.85 | KMT2A (0.53) | HTR1ADRD2KMT2AHSD17B10TARDBP | |
| SCHEMBL4252813 | 0.85 | KMT2A (0.53) | HTR1ADRD2KMT2AHSD17B10TARDBP | |
| SCHEMBL16870853 | 0.82 | KMT2A (0.45) | KMT2AHSD17B10TARDBPMEN1LMNA | |
| SCHEMBL16871077 | 0.78 | KMT2A (0.39) | KMT2AMEN1LMNAKDM4ETTR | |
| SCHEMBL16192774 | 0.74 | BCHE (0.41) | HTR1ADRD2KMT2AHSD17B10TARDBP | |
| SCHEMBL16192772 | 0.74 | BCHE (0.41) | HTR1ADRD2KMT2AHSD17B10TARDBP | |
| Dihydrolipoic Acid SCHEMBL8607573 | 0.74 | HSD17B10 (0.69) | KMT2AHSD17B10TARDBPMEN1LMNA | |
| SCHEMBL13197393 | 0.71 | HSD17B10 (0.50) | KMT2AHSD17B10TARDBPMEN1LMNA | |
| SCHEMBL16870898 | 0.70 | MAOB (0.46) | — | |
| SCHEMBL4259851 | 0.70 | MEN1 (0.45) | KMT2AHSD17B10TARDBPMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015095968-A1 | LIPOIC ACID-RESVERATROL CONJUGATES AND USES THEREOF | UNIVERSITY OF PRINCE EDWARD ISLAND (CA) | 2015-07-02 | — | — | WO | disclosed |