Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 9/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12739663 | 0.96 | CYP2C9 (0.33) | CYP2C9ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL12734852 | 0.96 | CYP2C9 (0.33) | CYP2C9ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL1242548 | 0.92 | OPRL1 (0.33) | OPRL1KDM1A | |
| SCHEMBL14922530 | 0.92 | OPRL1 (0.33) | OPRL1KDM1A | |
| SCHEMBL1242547 | 0.92 | OPRL1 (0.33) | OPRL1KDM1A | |
| SCHEMBL2604709 | 0.92 | CYP2C9 (0.38) | CYP2C9ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL18134228 | 0.92 | CYP2C9 (0.38) | CYP2C9ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL30665195 | 0.92 | CYP2C9 (0.38) | CYP2C9ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL3274912 | 0.92 | CYP2C9 (0.38) | CYP2C9ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL12733782 | 0.92 | CYP2C9 (0.38) | CYP2C9ALDH1A1MAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180112132-A1 | LIQUID CRYSTAL COMPOUNDS OF CYCLOALKYL-CONTAINING DIBENZOFURAN DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO.,LTD (CN) | 2018-04-26 | — | — | US | disclosed |
| US-9540565-B2 | Liquid crystal compounds containing dibenzopyran derivatives of naphthenic base and application thereof | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD (CN) | 2017-01-10 | — | — | US | disclosed |
| US-9540565-B2 | Liquid crystal compounds containing dibenzopyran derivatives of naphthenic base and application thereof | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD (CN) | 2017-01-10 | — | — | US | disclosed |
| US-9428693-B2 | Liquid crystal composition having negative dielectric anisotropy | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) | 2016-08-30 | — | — | US | disclosed |
| US-9428693-B2 | Liquid crystal composition having negative dielectric anisotropy | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) | 2016-08-30 | — | — | US | disclosed |
| US-20160230092-A1 | LIQUID CRYSTAL COMPOUNDS CONTAINING DIBENZOPYRAN DERIVATIVES OF NAPHTHENIC BASE AND APPLICATION THEREOF | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD (CN) | 2016-08-11 | — | — | US | disclosed |
| US-20160230092-A1 | LIQUID CRYSTAL COMPOUNDS CONTAINING DIBENZOPYRAN DERIVATIVES OF NAPHTHENIC BASE AND APPLICATION THEREOF | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD (CN) | 2016-08-11 | — | — | US | disclosed |
| US-20150184075-A1 | Liquid Crystal Composition Having Negative Dielectric Anisotropy | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) | 2015-07-02 | — | — | US | disclosed |
| US-20150184075-A1 | Liquid Crystal Composition Having Negative Dielectric Anisotropy | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) | 2015-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180112132-A1 | LIQUID CRYSTAL COMPOUNDS OF CYCLOALKYL-CONTAINING DIBENZOFURAN DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF | CYP4F11, WASF2, NOTUM | CYP2C9 486/4885ALDH1A1 640/4885MAPT 2141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.