SCHEMBL168724

SCHEMBL168724

CCCCCn1cc(O)c2ccccc21

nearest known ligand 0.59

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CDC25A P30304 1/20 0.59
ICMT O60725 1/20 0.58
CNR2 P34972 13/20 0.57
CNR1 P21554 10/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6475796 0.86 CNR2 (0.64) CDC25AICMTCNR2CNR1
SCHEMBL27977990 0.83 CNR2 (0.54) CDC25AICMTCNR2CNR1
SCHEMBL5462804 0.82 CDC25A (0.70) CDC25AICMTCNR2CNR1
SCHEMBL7712112 0.81 CNR2 (0.59) CDC25AICMTCNR2CNR1
SCHEMBL3262677 0.80 NR4A2 (0.54)
SCHEMBL7712109 0.80 CDC25A (0.56) CDC25AICMTCNR2CNR1
SCHEMBL8363931 0.80 CDC25A (0.59) CDC25AICMTCNR2CNR1
SCHEMBL14947367 0.80 CDC25A (0.59) CDC25AICMTCNR2CNR1
SCHEMBL13131369 0.80 CDC25A (0.72) CDC25AICMTCNR2CNR1
SCHEMBL27977988 0.79 CNR2 (0.56) CDC25AICMTCNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8940909-B2 Indicator platform BIOSYNTH AG (CH) 2015-01-27 US disclosed
EP-2427431-B1 NOVEL INDICATOR PLATFORM BIOSYNTH AG (CH) 2013-05-01 EP disclosed
EP-2427431-A1 NOVEL INDICATOR PLATFORM Biosynth AG (CH) 2012-03-14 EP disclosed
US-20120058503-A1 Novel Indicator Platform BIOSYNTH AG (CH) 2012-03-08 US disclosed
EP-2256103-A1 Novel indicator platform Biosynth AG (CH) 2010-12-01 EP disclosed
WO-2010128120-A1 NOVEL INDICATOR PLATFORM BIOSYNTH AG (CH) 2010-11-11 WO disclosed