Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16882815 | 0.92 | CDK4 (0.76) | CDK4CDK1 | |
| SCHEMBL16872561 | 0.90 | CDK4 (0.77) | CDK4CDK1 | |
| SCHEMBL15012106 | 0.90 | CDK4 (0.72) | CDK4CDK1 | |
| SCHEMBL2301687 | 0.90 | CDK4 (0.72) | CDK4CDK1 | |
| SCHEMBL2301691 | 0.90 | CDK4 (0.72) | CDK4CDK1 | |
| SCHEMBL12426734 | 0.90 | CDK4 (0.72) | CDK4CDK1 | |
| SCHEMBL15032353 | 0.90 | CDK4 (0.72) | CDK4CDK1 | |
| SCHEMBL16882804 | 0.89 | CDK4 (0.78) | CDK4CDK1 | |
| SCHEMBL15032360 | 0.89 | CDK4 (0.72) | CDK4CDK1 | |
| SCHEMBL2298920 | 0.89 | CDK4 (0.72) | CDK4CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2536730-B1 | PYRROLOPYRIMIDINE COMPOUNDS AS INHIBITORS OF CDK4/6 | NOVARTIS AG (CH) | 2015-07-08 | — | — | EP | disclosed |