SCHEMBL1687692

SCHEMBL1687692

C1=Cc2sc3c(-c4cccc(-c5cccc(-n6c7ccc(-c8ccccn8)cc7c7cc(-n8c9ccccc9c9ccccc98)ccc76)c5)c4)cccc3c2CC1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 1/20 0.33
HTR7 P34969 1/20 0.33
PRKDC P78527 1/20 0.32
GRM5 P41594 1/20 0.31
PIM1 P11309 1/20 0.30
PIM3 Q86V86 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1709171 0.88
SCHEMBL1709200 0.87 PRKDC (0.30) PRKDC
SCHEMBL16566404 0.86
SCHEMBL14136456 0.86 KDM4E (0.33)
SCHEMBL10064317 0.85
SCHEMBL10176092 0.84
SCHEMBL10064312 0.84 ALK (0.31)
SCHEMBL1709199 0.84
SCHEMBL10064745 0.84
SCHEMBL15838243 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012048266-A1 NOVEL 3, 9-LINKED OLIGOCARBAZOLE-BASED HOSTS, CONTAINING DBT AND DBR FRAGMENTS, SEPARATED BY AROMATIC SPACERS UNIVERSAL DISPLAY CORPORATION (US) 2012-04-12 WO disclosed