Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.75 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.75 |
| ▸ | PTPN9 | P43378 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.40 |
| ▸ | NPY4R | P50391 | 7/20 | 0.39 |
| ▸ | NPY1R | P25929 | 4/20 | 0.39 |
| ▸ | NPY2R | P49146 | 4/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.39 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1687880 | 0.97 | PTPN1 (0.78) | PTPN1PTPN2PTPN9ROCK2NPY4R | |
| SCHEMBL10237424 | 0.93 | PTPN1 (0.65) | PTPN1PTPN2PTPN9ALBNPY4R | |
| SCHEMBL10235361 | 0.91 | PTPN1 (0.61) | PTPN1PTPN2PTPN9ALBNPY4R | |
| SCHEMBL7881120 | 0.86 | PTPN1 (0.62) | PTPN1PTPN2PTPN9 | |
| SCHEMBL7883486 | 0.86 | PTPN1 (0.62) | PTPN1PTPN2PTPN9ROCK2NPY4R | |
| SCHEMBL7886025 | 0.83 | PTPN1 (0.69) | PTPN1PTPN2PTPN9 | |
| SCHEMBL7874752 | 0.83 | PTPN1 (0.59) | PTPN1PTPN2PTPN9 | |
| SCHEMBL1687796 | 0.81 | PTPN1 (0.85) | PTPN1PTPN2PTPN9ROCK2NPY4R | |
| SCHEMBL7881108 | 0.81 | PTPN1 (0.85) | PTPN1PTPN2PTPN9ROCK2NPY4R | |
| SCHEMBL10237734 | 0.79 | PTPN1 (0.51) | PTPN1PTPN2PTPN9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160176922-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | Indiana University Research and Technology Corpora tion (US) | 2016-06-23 | — | — | US | disclosed |
| US-9217012-B2 | Inhibitors of protein tyrosine phosphatases | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2015-12-22 | — | — | US | disclosed |
| US-20120088720-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATI (US) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160176922-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | PTPRCAP, PTPRF, PTPRS | PTPN1 20/4885PTPN2 26/4885PTPN9 34/4885 |
| US-20120088720-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | PTPRCAP, PTPRF, PTPRS | PTPN1 20/4885PTPN2 26/4885PTPN9 34/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.