Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | MMP8 | P22894 | 10/20 | 0.46 |
| ▸ | MMP3 | P08254 | 5/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16879298 | 1.00 | PTPN1 (0.57) | PTPN1HDAC8OPRM1OPRD1OPRK1 | |
| SCHEMBL7536598 | 0.90 | PTPN1 (0.71) | PTPN1HDAC8 | |
| SCHEMBL19329100 | 0.90 | PTPN1 (0.71) | PTPN1HDAC8 | |
| SCHEMBL19329065 | 0.86 | PTPN1 (0.50) | PTPN1HDAC8OPRM1OPRD1OPRK1 | |
| SCHEMBL1201702 | 0.85 | PTPN1 (0.65) | PTPN1HDAC8 | |
| SCHEMBL19329075 | 0.84 | PTPN1 (0.55) | PTPN1HDAC8PDE4BPDE4D | |
| SCHEMBL29780698 | 0.84 | PTPN1 (0.55) | PTPN1HDAC8PDE4BPDE4D | |
| SCHEMBL16879098 | 0.84 | PTPN1 (0.55) | PTPN1HDAC8OPRM1OPRD1OPRK1 | |
| SCHEMBL16879099 | 0.84 | PTPN1 (0.55) | PTPN1HDAC8OPRM1OPRD1OPRK1 | |
| SCHEMBL9849305 | 0.84 | PTPN1 (0.55) | PTPN1HDAC8PDE4BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015103527-A1 | MODULATORS OF REV-ERB | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-07-09 | — | — | WO | disclosed |