Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.77 |
| ▸ | CA12 | O43570 | 2/20 | 0.72 |
| ▸ | CA1 | P00915 | 2/20 | 0.72 |
| ▸ | CA2 | P00918 | 2/20 | 0.72 |
| ▸ | CA9 | Q16790 | 2/20 | 0.72 |
| ▸ | RORC | P51449 | 10/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1102036 | 0.85 | ATM (0.77) | ATMCA12CA1CA2CA9 | |
| SCHEMBL13589490 | 0.85 | ATM (0.77) | ATMCA12CA1CA2CA9 | |
| SCHEMBL11883912 | 0.85 | POLB (0.69) | CA12CA1CA2CA9MAPT | |
| SCHEMBL13989319 | 0.84 | GAA (0.73) | ATMCA12CA1CA2CA9 | |
| SCHEMBL3906876 | 0.84 | ATM (0.74) | ATMCA12CA1CA2CA9 | |
| SCHEMBL3906878 | 0.84 | ATM (0.74) | ATMCA12CA1CA2CA9 | |
| SCHEMBL13263684 | 0.84 | CA1 (1.00) | ATMCA12CA1CA2CA9 | |
| SCHEMBL1102000 | 0.84 | ATM (0.74) | ATMCA12CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL27809978 | 0.84 | ATM (0.74) | ATMCA12CA1CA2CA9 | |
| SCHEMBL8231658 | 0.82 | ATM (0.72) | ATMCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015101928-A1 | FUSED THIOPHENE AND THIAZOLE DERIVATIVES AS ROR GAMMA MODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2015-07-09 | — | — | WO | disclosed |