SCHEMBL1688103

SCHEMBL1688103

O=C(O)CCCCCCCCCCSC(C(=O)NCCNC(=O)c1ccc(-c2c3ccc(=O)cc-3oc3cc(O)ccc23)c(C(=O)O)c1)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 2/20 0.55
▸ ALB P02768 2/20 0.49
▸ HTRA2 O43464 6/20 0.49
▸ HTRA1 Q92743 6/20 0.49
▸ SLC5A2 P31639 2/20 0.48
▸ USP2 O75604 1/20 0.47
▸ L3MBTL1 Q9Y468 1/20 0.47
▸ CA9 Q16790 1/20 0.47
▸ AVPR2 P30518 1/20 0.46
▸ OXTR P30559 1/20 0.46
▸ AVPR1A P37288 1/20 0.46
▸ ESR1 P03372 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18699631 0.91 ALB (0.56) FOLH1ALBHTRA2HTRA1SLC5A2
SCHEMBL14402543 0.90 FOLH1 (0.48) FOLH1ALBHTRA2HTRA1SLC5A2
SCHEMBL14402763 0.90 FOLH1 (0.48) FOLH1ALBHTRA2HTRA1SLC5A2
SCHEMBL9906219 0.90 FOLH1 (0.49) FOLH1ALBHTRA2HTRA1SLC5A2
SCHEMBL14402762 0.85 ALB (0.49) FOLH1ALBHTRA2HTRA1SLC5A2
SCHEMBL16295184 0.85 FOLH1 (0.68) FOLH1ALBHTRA2HTRA1SLC5A2
SCHEMBL9906147 0.85 FOLH1 (0.46) FOLH1ALBHTRA2HTRA1SLC5A2
SCHEMBL13780500 0.83 USP2 (0.55) FOLH1ALBHTRA2HTRA1SLC5A2
SCHEMBL14525869 0.83 USP2 (0.55) FOLH1ALBHTRA2HTRA1SLC5A2
SCHEMBL13678641 0.83 ALB (0.48) FOLH1ALBHTRA2HTRA1SLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1673399-B1 DETECTING AND PROFILING MOLECULAR COMPLEXES MONOGRAM BIOSCIENCES INC (US) 2017-04-05 — — EP disclosed
US-9110075-B2 Compositions for analyzing proteins MONOGRAM BIOSCIENCES, INC. (US) 2015-08-18 — — US disclosed
US-8198031-B2 Using epidermal growth factor receptor complexes to diagnose and prognose health in cancer patients; drug screening MONOGRAM BIOSCIENCES, INC. (US) 2012-06-12 — — US disclosed
US-20120088307-A1 Methods and Compositions for Analyzing Proteins MONOGRAM BIOSCIENCES, INC. (US) 2012-04-12 — — US disclosed
US-20090173631-A1 Single Cell Analysis of Membrane Molecules ACLARA BIOSCIENCES, INC. 2009-07-09 — — US disclosed
US-20090011432-A1 Detecting and Profiling Molecular Complexes MONOGRAM BIOSCIENCES, INC. (US) 2009-01-08 — — US disclosed
US-20080311674-A1 METHODS AND COMPOSITIONS FOR ANALYZING PROTEINS MONOGRAM BIOSCIENCES, INC. (US) 2008-12-18 — — US disclosed
US-20080233602-A1 Detecting and profiling molecular complexes MONOGRAM BIOSCIENCES, INC. 2008-09-25 — — US disclosed
US-7402397-B2 Detecting and profiling molecular complexes MONOGRAM BIOSCIENCES, INC. (US) 2008-07-22 — — US disclosed
US-7279585-B2 Lipophilic electrophoretic probes MONOGRAM BIOSCIENCES, INC. (US) 2007-10-09 — — US disclosed
US-7255999-B2 Detection of preferential polypetide in sample; otain sample containing preferential polyeptide, electrophorese, incubate with probe, detect signal from probe and recover polypeptide MONOGRAM BIOSCIENCES, INC. (US) 2007-08-14 — — US disclosed
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