Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 2/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL97584 | 0.87 | CCNE2 (0.46) | CCNE2CCNE1CDK2NPC1RAB9A | |
| SCHEMBL97557 | 0.85 | CCNE2 (0.44) | CCNE2CCNE1CDK2NPC1RAB9A | |
| SCHEMBL97888 | 0.85 | CCNE2 (0.44) | CCNE2CCNE1CDK2NPC1RAB9A | |
| SCHEMBL100715 | 0.84 | CCNE2 (0.47) | CCNE2CCNE1CDK2NPC1RAB9A | |
| SCHEMBL100247 | 0.82 | CCNE2 (0.41) | CCNE2CCNE1CDK2NPC1RAB9A | |
| SCHEMBL97640 | 0.82 | CCNE2 (0.41) | CCNE2CCNE1CDK2NPC1RAB9A | |
| SCHEMBL98553 | 0.80 | CCNE2 (0.44) | CCNE2CCNE1CDK2NPC1RAB9A | |
| SCHEMBL98749 | 0.77 | CCNE2 (0.54) | CCNE2CCNE1CDK2NPC1RAB9A | |
| SCHEMBL97934 | 0.77 | CCNE2 (0.46) | CCNE2CCNE1CDK2NPC1RAB9A | |
| SCHEMBL98797 | 0.76 | CCNE2 (0.45) | CCNE2CCNE1CDK2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426130-A1 | PURINE DERIVATIVE AND ANTITUMOR AGENT USING SAME | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 2012-03-07 | — | — | EP | disclosed |