Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.45 |
| ▸ | BTK | Q06187 | 14/20 | 0.43 |
| ▸ | NUDT14 | O95848 | 1/20 | 0.41 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 5/20 | 0.39 |
| ▸ | LCK | P06239 | 4/20 | 0.39 |
| ▸ | ITK | Q08881 | 3/20 | 0.39 |
| ▸ | BMX | P51813 | 3/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | JAK3 | P52333 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 5/20 | 0.38 |
| ▸ | FGR | P09769 | 4/20 | 0.38 |
| ▸ | YES1 | P07947 | 3/20 | 0.38 |
| ▸ | LYN | P07948 | 4/20 | 0.38 |
| ▸ | FLT3 | P36888 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15613563 | 0.91 | KCNH2 (0.53) | KCNH2PIK3CAPIK3CGBTKNUDT14 | |
| SCHEMBL15613644 | 0.87 | KCNH2 (0.55) | KCNH2PIK3CAPIK3CGBTKNUDT14 | |
| SCHEMBL16886202 | 0.87 | KCNH2 (0.55) | KCNH2PIK3CAPIK3CGBTKNUDT14 | |
| SCHEMBL15613565 | 0.86 | KCNH2 (0.54) | KCNH2PIK3CAPIK3CGBTKNUDT14 | |
| SCHEMBL15613567 | 0.86 | KCNH2 (0.56) | KCNH2PIK3CAPIK3CGBTKNUDT14 | |
| SCHEMBL16886190 | 0.83 | CYP1A2 (0.47) | PIK3CAPIK3CGBTKNUDT14NUDT5 | |
| SCHEMBL15613538 | 0.76 | SRC (0.48) | PIK3CAPIK3CGBTKNUDT14NUDT5 | |
| SCHEMBL15613656 | 0.75 | CYP1A2 (0.46) | PIK3CAPIK3CGBTKNUDT14NUDT5 | |
| SCHEMBL16886171 | 0.74 | SRC (0.50) | PIK3CABTKNUDT14NUDT5FYN | |
| SCHEMBL16886182 | 0.74 | SRC (0.49) | PIK3CAPIK3CGBTKNUDT14NUDT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796716-B2 | Selective inhibitors of Tec and Src protein kinase families | PHARMASCIENCE, INC. (CA) | 2017-10-24 | — | — | US | disclosed |
| US-20150191473-A1 | PROTEIN KINASE INHIBITORS | PHARMASCIENCE, INC. (CA) | 2015-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150191473-A1 | PROTEIN KINASE INHIBITORS | TEC, SRC, LCK | KCNH2 4209/4885PIK3CA 414/4885PIK3CG 449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.