Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GCK | P35557 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16879917 | 0.86 | BRD4 (0.38) | ALDH1A1KDM4EPSIP1KMT2AGCK | |
| SCHEMBL16888067 | 0.82 | CA12 (0.43) | ALDH1A1KDM4EMAPTKMT2ATDP1 | |
| SCHEMBL4591705 | 0.75 | KDM4E (0.56) | ALDH1A1POLBKDM4EMAPTHDAC6 | |
| SCHEMBL22114351 | 0.71 | HDAC6 (0.45) | ALDH1A1POLBKDM4EMAPTHDAC6 | |
| SCHEMBL17512273 | 0.71 | HDAC6 (0.45) | ALDH1A1POLBKDM4EMAPTHDAC6 | |
| SCHEMBL15469125 | 0.71 | HDAC6 (0.45) | ALDH1A1POLBKDM4EMAPTHDAC6 | |
| SCHEMBL13674230 | 0.69 | KMT2A (0.49) | ALDH1A1POLBKDM4EKMT2ACYP1A2 | |
| SCHEMBL13674231 | 0.69 | KMT2A (0.49) | POLBMAPTKMT2ARORC | |
| SCHEMBL20541532 | 0.68 | HDAC6 (0.45) | ALDH1A1POLBKDM4EMAPTHDAC6 | |
| SCHEMBL17313824 | 0.68 | HDAC6 (0.42) | ALDH1A1POLBKDM4EMAPTHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015101928-A1 | FUSED THIOPHENE AND THIAZOLE DERIVATIVES AS ROR GAMMA MODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2015-07-09 | — | — | WO | disclosed |