SCHEMBL16888447

SCHEMBL16888447

C/C=C(\O)c1c2c(nc3sc(C(N)=O)c(N)c13)C(C)(C)CC2

nearest known ligand 0.65

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EEF2K O00418 20/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16888398 0.80 EEF2K (0.59) EEF2K
SCHEMBL16888451 0.79 EEF2K (1.00) EEF2K
SCHEMBL16888456 0.76 EEF2K (1.00) EEF2K
SCHEMBL16888415 0.75 EEF2K (1.00) EEF2K
SCHEMBL16888446 0.74 EEF2K (1.00) EEF2K
SCHEMBL16888450 0.74 EEF2K (1.00) EEF2K
SCHEMBL16888417 0.74 EEF2K (1.00) EEF2K
SCHEMBL16888459 0.74 EEF2K (1.00) EEF2K
SCHEMBL16888442 0.74 EEF2K (1.00) EEF2K
SCHEMBL16888457 0.74 EEF2K (1.00) EEF2K

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015102752-A1 COMPOUNDS INHIBITING EUKARYOTIC ELONGATION FACTOR 2 KINASE ACTIVITY LONGEVICA PHARMACEUTICALS, INC. (US) 2015-07-09 WO disclosed