Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3364990 | 0.84 | CYP3A4 (0.45) | CYP3A4TRPA1TDP1ALDH1A1HPGD | |
| SCHEMBL645833 | 0.81 | CYP3A4 (0.50) | CYP3A4TRPA1TDP1ALDH1A1HPGD | |
| SCHEMBL30519851 | 0.81 | CYP3A4 (0.50) | CYP3A4TRPA1TDP1ALDH1A1HPGD | |
| SCHEMBL2489721 | 0.79 | CYP3A4 (0.48) | CYP3A4TRPA1TDP1ALDH1A1HPGD | |
| SCHEMBL31597 | 0.79 | CYP3A4 (0.68) | CYP3A4TRPA1TDP1ALDH1A1HPGD | |
| SCHEMBL27918564 | 0.78 | CYP3A4 (0.47) | CYP3A4TRPA1TDP1ALDH1A1HPGD | |
| SCHEMBL9248539 | 0.77 | CYP3A4 (0.39) | CYP3A4TRPA1TDP1ALDH1A1HPGD | |
| SCHEMBL11667358 | 0.76 | CYP3A4 (0.48) | CYP3A4TRPA1TDP1ALDH1A1HPGD | |
| SCHEMBL3786089 | 0.76 | NPC1 (0.52) | CYP3A4TRPA1TDP1ALDH1A1HPGD | |
| SCHEMBL58424 | 0.76 | CYP3A4 (0.45) | CYP3A4TRPA1TDP1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150197641-A1 | CAVITATION RESISTANT POLYURETHANE COMPOSITIONS AND METHODS OF FORMING COATING FILMS USING THE SAME | NOROO PAINT & COATINGS CO., LTD. (KR) | 2015-07-16 | — | — | US | claimed |
| US-9255204-B2 | Cavitation resistant polyurethane compositions and methods of forming coating films using the same | NOROO HOLDINGS CO., LTD (KR) | 2016-02-09 | — | — | US | disclosed |
| US-20150197641-A1 | CAVITATION RESISTANT POLYURETHANE COMPOSITIONS AND METHODS OF FORMING COATING FILMS USING THE SAME | NOROO PAINT & COATINGS CO., LTD. (KR) | 2015-07-16 | — | — | US | disclosed |