Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 5/20 | 0.39 |
| ▸ | UGCG | Q16739 | 5/20 | 0.39 |
| ▸ | GBA2 | Q9HCG7 | 5/20 | 0.39 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | LCT | P09848 | 2/20 | 0.34 |
| ▸ | SI | P14410 | 2/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL28769321 | 0.80 | GAA (0.33) | GAAMGAM | |
| SCHEMBL17580442 | 0.79 | GAA (0.42) | GBA1UGCGGBA2GAALCT | |
| SCHEMBL10351758 | 0.77 | CDK1 (0.40) | PDE4DCYP2C19SLC6A2 | |
| SCHEMBL6707887 | 0.74 | — | — | |
| SCHEMBL28680328 | 0.74 | — | — | |
| SCHEMBL11218188 | 0.74 | GAA (0.34) | GAAMGAM | |
| SCHEMBL28248118 | 0.74 | GAA (0.34) | GAAMGAM | |
| SCHEMBL11153956 | 0.74 | GAA (0.34) | GAAMGAM | |
| SCHEMBL8726694 | 0.73 | — | — | |
| SCHEMBL11146581 | 0.73 | MGAM (0.30) | GAAMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180180626-A1 | A METHOD FOR DEVELOPMENT OF RECOMBINANT PROTEINS WITH FINGERPRINT LIKE SIMILARITY TO THE REFERENCE PRODUCT | STC BIOLOGICS INC (US) | 2018-06-28 | — | — | US | disclosed |
| US-9868973-B2 | Method for optimizing post-translational modifications on recombinant proteins | STC BIOLOGICS, INC. (US) | 2018-01-16 | — | — | US | disclosed |
| US-20160340706-A1 | Method for Optimizing Post-Translational Modifications on Recombinant Proteins | STC BIOLOGICS, INC. | 2016-11-24 | — | — | US | disclosed |
| EP-3094639-A1 | METHOD FOR OPTIMIZING POST-TRANSLATIONAL MODIFICATIONS ON RECOMBINANT PROTEINS | Leszcyniecka, Magdalena (US) | 2016-11-23 | — | — | EP | disclosed |
| WO-2015106276-A1 | METHOD FOR OPTIMIZING POST-TRANSLATIONAL MODIFICATIONS ON RECOMBINANT PROTEINS | LESZCYNIECKA MAGDALENA (US) | 2015-07-16 | — | — | WO | disclosed |