Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 20/20 | 0.75 |
| ▸ | BCR | P11274 | 19/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16898735 | 1.00 | ABL1 (0.75) | ABL1BCRKDM4EMAPTMAPK1 | |
| SCHEMBL16898654 | 0.92 | ABL1 (0.78) | ABL1BCRKDM4EMAPTMAPK1 | |
| SCHEMBL16898190 | 0.92 | ABL1 (0.78) | ABL1BCRKDM4EMAPTMAPK1 | |
| SCHEMBL16898602 | 0.92 | ABL1 (0.78) | ABL1BCRKDM4EMAPTMAPK1 | |
| SCHEMBL16898475 | 0.91 | ABL1 (0.72) | ABL1BCRKDM4EMAPTMAPK1 | |
| SCHEMBL16898538 | 0.91 | ABL1 (0.72) | ABL1BCRKDM4EMAPTMAPK1 | |
| SCHEMBL16898701 | 0.91 | ABL1 (0.72) | ABL1BCRKDM4EMAPTMAPK1 | |
| SCHEMBL16898494 | 0.91 | ABL1 (0.72) | ABL1BCRKDM4EMAPTMAPK1 | |
| SCHEMBL16898548 | 0.91 | ABL1 (0.77) | ABL1BCRKDM4EMAPTMAPK1 | |
| SCHEMBL16898729 | 0.91 | ABL1 (0.77) | ABL1BCRKDM4EMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015106292-A1 | BCR-ABL TYROSINE-KINASE LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2015-07-16 | — | — | WO | claimed |
| WO-2015106292-A1 | BCR-ABL TYROSINE-KINASE LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2015-07-16 | — | — | WO | disclosed |
| WO-2015106292-A1 | BCR-ABL TYROSINE-KINASE LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2015-07-16 | — | — | WO | disclosed |