Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13863428 | 1.00 | MEN1 (0.38) | MEN1KMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL16426456 | 1.00 | MEN1 (0.38) | MEN1KMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL16898642 | 1.00 | MEN1 (0.38) | MEN1KMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL19726769 | 1.00 | MEN1 (0.38) | MEN1KMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL31273755 | 1.00 | MEN1 (0.38) | MEN1KMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL121824 | 0.96 | KDM4E (0.38) | MEN1KMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL12748073 | 0.90 | KDM4E (0.34) | KDM4EALDH1A1TSHRPOLBALOX15 | |
| SCHEMBL24183422 | 0.89 | KDM4E (0.42) | MEN1KMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL19689426 | 0.89 | KDM4E (0.42) | MEN1KMT2AKDM4EALDH1A1TSHR | |
| SCHEMBL15462770 | 0.86 | KDM4E (0.36) | MEN1KMT2AKDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015106292-A1 | BCR-ABL TYROSINE-KINASE LIGANDS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME | COFERON, INC. (US) | 2015-07-16 | — | — | WO | disclosed |