Bromacil

Bromacil

SCHEMBL16899690

CCC(C)n1c(=O)[nH]c(C)c(Br)c1=O.CCC(C)n1c(=O)[nH]c(C)c(Br)c1=O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ GRIA1 P42261 1/20 0.32
▸ GRIA2 P42262 1/20 0.32
▸ GRIA3 P42263 1/20 0.32
▸ GRIA4 P48058 1/20 0.32
▸ POLB P06746 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromacil SCHEMBL28449642 0.98 GRIA1 (0.31) GRIA1GRIA2GRIA3GRIA4POLB
Bromacil SCHEMBL29827179 0.98 GRIA1 (0.31) GRIA1GRIA2GRIA3GRIA4POLB
Bromacil SCHEMBL28645226 0.98 GRIA1 (0.31) GRIA1GRIA2GRIA3GRIA4POLB
Bromacil SCHEMBL28030572 0.98 GRIA1 (0.31) GRIA1GRIA2GRIA3GRIA4POLB
Bromacil SCHEMBL28373932 0.98 GRIA1 (0.31) GRIA1GRIA2GRIA3GRIA4POLB
Bromacil SCHEMBL28338910 0.98 ATM (0.31) GRIA1GRIA2GRIA3GRIA4POLB
SCHEMBL11323982 0.84 MAPT (0.35) POLBMAPT
Bromacil SCHEMBL8827477 0.83 — —
SCHEMBL11322386 0.82 TSHR (0.32) TSHR
Bromacil SCHEMBL8388251 0.82 KDM4E (0.31) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020011127-A1 MUTANT PSII D1 OR PSBA D1 PROTEIN, CODING NUCLEIC ACID THEREOF AND USE THEREOF 青岛清原化合物有限公司 2020-01-16 — — WO disclosed
EP-3092310-A1 RNA-GUIDED GENE DRIVES President and Fellows of Harvard College (US) 2016-11-16 — — EP disclosed
WO-2015105928-A9 RNA-GUIDED GENE DRIVES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2015-09-24 — — WO disclosed
WO-2015105928-A1 RNA-GUIDED GENE DRIVES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2015-07-16 — — WO disclosed
CN-86100691-A The Herbicidal mixture of N-((phosphonomethyl) glycyl) sulfonamide type compound — 1986-12-03 — — CN disclosed
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