Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 20/20 | 1.00 |
| ▸ | PDE5A | O76074 | 5/20 | 1.00 |
| ▸ | PDE3B | Q13370 | 5/20 | 1.00 |
| ▸ | PDE11A | Q9HCR9 | 5/20 | 1.00 |
| ▸ | PDE7B | Q9NP56 | 5/20 | 1.00 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 1.00 |
| ▸ | PDE2A | O00408 | 4/20 | 1.00 |
| ▸ | PDE8A | O60658 | 4/20 | 1.00 |
| ▸ | PDE9A | O76083 | 3/20 | 1.00 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.74 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.74 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.74 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL772857 | 1.00 | PDE4A (1.00) | PDE4APDE5APDE3BPDE11APDE7B | |
| SCHEMBL4920045 | 0.98 | PDE4A (0.97) | PDE4APDE5APDE3BPDE11APDE7B | |
| SCHEMBL19159222 | 0.98 | PDE4A (0.95) | PDE4APDE5APDE3BPDE11APDE7B | |
| SCHEMBL10201367 | 0.92 | PDE4A (0.86) | PDE4APDE5APDE3BPDE11APDE7B | |
| SCHEMBL773887 | 0.92 | PDE4A (0.84) | PDE4APDE5APDE3BPDE11APDE7B | |
| SCHEMBL4920743 | 0.91 | PDE4A (1.00) | PDE4APDE5APDE3BPDE11APDE7B | |
| SCHEMBL19134017 | 0.91 | PDE4A (1.00) | PDE4APDE5APDE3BPDE11APDE7B | |
| SCHEMBL8046132 | 0.91 | PDE4A (1.00) | PDE4APDE5APDE3BPDE11APDE7B | |
| SCHEMBL8245508 | 0.91 | PDE4A (0.83) | PDE4APDE5APDE3BPDE11APDE7B | |
| SCHEMBL8058077 | 0.90 | PDE4A (0.86) | PDE4APDE5APDE3BPDE11APDE7B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3091983-A1 | PRODUCTS AND PHARMACEUTICAL COMPOSITIONS | Intra-Cellular Therapies, Inc. (US) | 2016-11-16 | — | — | EP | claimed |
| WO-2015106032-A1 | PRODUCTS AND PHARMACEUTICAL COMPOSITIONS | INTRA-CELLULAR THERAPIES, INC. (US) | 2015-07-16 | — | — | WO | claimed |
| EP-4017858-A1 | ORGANIC COMPOUNDS | Intra-Cellular Therapies, Inc. (US) | 2022-06-29 | — | — | EP | disclosed |
| WO-2021035157-A1 | ORGANIC COMPOUNDS | INTRA-CELLULAR THERAPIES, INC. (US) | 2021-02-25 | — | — | WO | disclosed |
| WO-2020160037-A1 | NOVEL DEVICES | INTRA-CELLULAR THERAPIES, INC. (US) | 2020-08-06 | — | — | WO | disclosed |
| EP-3091983-A1 | PRODUCTS AND PHARMACEUTICAL COMPOSITIONS | Intra-Cellular Therapies, Inc. (US) | 2016-11-16 | — | — | EP | disclosed |
| WO-2015106032-A1 | PRODUCTS AND PHARMACEUTICAL COMPOSITIONS | INTRA-CELLULAR THERAPIES, INC. (US) | 2015-07-16 | — | — | WO | disclosed |