Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 20/20 | 0.59 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.48 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6341459 | 0.94 | PDE9A (0.61) | PDE9A | |
| SCHEMBL16900033 | 0.91 | PDE9A (0.62) | PDE9APDE1C | |
| SCHEMBL16900052 | 0.87 | PDE9A (0.58) | PDE9APDE1C | |
| SCHEMBL16900055 | 0.87 | PDE9A (0.63) | PDE9APDE1C | |
| SCHEMBL6338426 | 0.84 | PDE9A (0.65) | PDE9A | |
| SCHEMBL16900057 | 0.83 | PDE9A (0.59) | PDE9APDE1C | |
| SCHEMBL16900030 | 0.83 | PDE9A (0.55) | PDE9APDE1C | |
| SCHEMBL16900050 | 0.83 | PDE9A (0.65) | PDE9A | |
| SCHEMBL16900027 | 0.82 | PDE9A (0.76) | PDE9APDE1CPDE1B | |
| SCHEMBL6340787 | 0.82 | PDE9A (0.67) | PDE9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9079905-B2 | Compounds for the treatment of CNS disorders | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-07-14 | — | — | US | disclosed |