Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 20/20 | 0.64 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6342437 | 0.94 | PDE9A (0.65) | PDE9A | |
| SCHEMBL16900091 | 0.91 | PDE9A (0.76) | PDE9A | |
| SCHEMBL16900066 | 0.87 | PDE9A (0.64) | PDE9APDE1C | |
| SCHEMBL16900060 | 0.87 | PDE9A (0.64) | PDE9APDE1C | |
| SCHEMBL16900073 | 0.87 | PDE9A (0.55) | PDE9A | |
| SCHEMBL16900077 | 0.86 | PDE9A (0.66) | PDE9A | |
| SCHEMBL16900058 | 0.86 | PDE9A (0.65) | PDE9APDE1C | |
| SCHEMBL16900087 | 0.86 | PDE9A (0.63) | PDE9APDE1C | |
| SCHEMBL6343669 | 0.85 | PDE9A (0.78) | PDE9A | |
| SCHEMBL16900088 | 0.84 | PDE9A (0.80) | PDE9APDE1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9079905-B2 | Compounds for the treatment of CNS disorders | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-07-14 | — | — | US | disclosed |