Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 20/20 | 0.59 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6342453 | 0.94 | PDE9A (0.61) | PDE9APDE1C | |
| SCHEMBL16900083 | 0.89 | PDE9A (0.76) | PDE9APDE1C | |
| SCHEMBL16900075 | 0.84 | PDE9A (0.54) | PDE9APDE1C | |
| SCHEMBL16900078 | 0.84 | PDE9A (0.65) | PDE9APDE1C | |
| SCHEMBL16900080 | 0.82 | PDE9A (0.61) | PDE9APDE1C | |
| SCHEMBL6342458 | 0.82 | PDE9A (0.78) | PDE9APDE1C | |
| SCHEMBL6369795 | 0.81 | PDE9A (0.60) | PDE9APDE1C | |
| SCHEMBL6368974 | 0.79 | PDE9A (0.59) | PDE9APDE1C | |
| SCHEMBL16900091 | 0.79 | PDE9A (0.76) | PDE9A | |
| SCHEMBL6342712 | 0.78 | PDE9A (0.56) | PDE9APDE1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9079905-B2 | Compounds for the treatment of CNS disorders | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-07-14 | — | — | US | disclosed |