Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 19/20 | 0.82 |
| ▸ | MTOR | P42345 | 16/20 | 0.82 |
| ▸ | PIK3R1 | P27986 | 11/20 | 0.82 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.54 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.54 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | RICTOR | Q6R327 | 4/20 | 0.51 |
| ▸ | RPTOR | Q8N122 | 4/20 | 0.51 |
| ▸ | MAPKAP1 | Q9BPZ7 | 4/20 | 0.51 |
| ▸ | MLST8 | Q9BVC4 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1309506 | 0.91 | PIK3CA (1.00) | PIK3CAMTORPIK3R1PIK3CDPIK3CG | |
| SCHEMBL15386446 | 0.84 | PIK3CA (0.77) | PIK3CAMTORPIK3R1PIK3CDPIK3CG | |
| SCHEMBL18193210 | 0.84 | PIK3CA (0.85) | PIK3CAMTORPIK3R1PIK3CDPIK3CG | |
| SCHEMBL29434910 | 0.84 | PIK3CA (0.85) | PIK3CAMTORPIK3R1PIK3CDPIK3CG | |
| SCHEMBL18771918 | 0.81 | PIK3CA (0.77) | PIK3CAMTORPIK3R1PIK3CDPIK3CG | |
| SCHEMBL2438086 | 0.81 | PIK3CA (0.79) | PIK3CAMTORPIK3R1PIK3CDPIK3CG | |
| SCHEMBL1309220 | 0.80 | PIK3CA (0.70) | PIK3CAMTORPIK3R1PIK3CDPIK3CG | |
| SCHEMBL910089 | 0.79 | PIK3CA (0.71) | PIK3CAMTORPIK3R1PIK3CDPIK3CG | |
| SCHEMBL10328141 | 0.79 | PIK3CA (0.72) | PIK3CAMTORPIK3R1PIK3CDRICTOR | |
| SCHEMBL7999965 | 0.78 | PIK3CA (0.74) | PIK3CAMTORPIK3R1PIK3CDPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9630958-B2 | Triazine compounds | SPHAERA PHARMA PTE. LTD. (SG) | 2017-04-25 | — | — | US | disclosed |
| US-20150197515-A1 | NOVEL TRIAZINE COMPOUNDS | SPHAERA PHARMA PTE. LTD. (SG) | 2015-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150197515-A1 | NOVEL TRIAZINE COMPOUNDS | MTOR, PIK3R5, PIK3R2 | PIK3CA 23/4885MTOR 1/4885PIK3R1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.