Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 6/20 | 0.34 |
| ▸ | DHODH | Q02127 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29360347 | 0.85 | DHODH (0.40) | MALT1DHODHLRRK2 | |
| SCHEMBL13335092 | 0.85 | DHODH (0.35) | MALT1DHODHLRRK2 | |
| SCHEMBL29458550 | 0.85 | DHODH (0.40) | MALT1DHODHLRRK2 | |
| SCHEMBL123506 | 0.85 | DHODH (0.40) | MALT1DHODHLRRK2 | |
| SCHEMBL13318643 | 0.83 | MALT1 (0.33) | MALT1DHODHLRRK2 | |
| SCHEMBL30674784 | 0.80 | DHODH (0.37) | MALT1DHODH | |
| SCHEMBL31628519 | 0.77 | DHODH (0.38) | MALT1DHODHLRRK2 | |
| SCHEMBL326444 | 0.77 | DHODH (0.38) | MALT1DHODHLRRK2 | |
| SCHEMBL14961243 | 0.77 | MALT1 (0.36) | MALT1DHODH | |
| SCHEMBL17750084 | 0.77 | DHODH (0.39) | MALT1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2459569-B1 | INSECTICIDAL 4-AMINO-THIENO[2,3-D]-PYRIMIDINE COMPOUNDS AND METHODS OF THEIR USE | MERIAL INC (US) | 2015-07-22 | — | — | EP | disclosed |