Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 1.00 |
| ▸ | TP53 | P04637 | 2/20 | 1.00 |
| ▸ | NPC1 | O15118 | 8/20 | 0.79 |
| ▸ | RAB9A | P51151 | 8/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.79 |
| ▸ | PKM | P14618 | 2/20 | 0.75 |
| ▸ | GAA | P10253 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | GFER | P55789 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | MITF | O75030 | 1/20 | 0.64 |
| ▸ | KDM5A | P29375 | 1/20 | 0.64 |
| ▸ | KDM5C | P41229 | 1/20 | 0.64 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13325910 | 0.96 | SMN1; SMN2 (0.93) | SMN1; SMN2TP53NPC1RAB9AKDM4E | |
| SCHEMBL13325899 | 0.89 | SMN1; SMN2 (0.79) | SMN1; SMN2TP53NPC1RAB9AKDM4E | |
| SCHEMBL4727165 | 0.89 | SMN1; SMN2 (0.79) | SMN1; SMN2TP53NPC1RAB9AKDM4E | |
| SCHEMBL10648324 | 0.89 | SMN1; SMN2 (0.79) | SMN1; SMN2TP53NPC1RAB9AKDM4E | |
| SCHEMBL4727102 | 0.89 | SMN1; SMN2 (0.79) | SMN1; SMN2TP53NPC1RAB9AKDM4E | |
| SCHEMBL972809 | 0.89 | NPC1 (1.00) | SMN1; SMN2TP53NPC1RAB9AKDM4E | |
| SCHEMBL6393875 | 0.88 | SMN1; SMN2 (0.79) | SMN1; SMN2TP53NPC1RAB9AKDM4E | |
| Bromide SCHEMBL1691396 | 0.87 | NPC1 (0.97) | SMN1; SMN2TP53NPC1RAB9AKDM4E | |
| SCHEMBL15207138 | 0.87 | SMN1; SMN2 (0.77) | SMN1; SMN2TP53NPC1RAB9AKDM4E | |
| SCHEMBL13325751 | 0.86 | TP53 (0.75) | SMN1; SMN2TP53NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200062719-A1 | Application of Imidazopyridine Derivatives in Regenerative Medicine | UNIVERSITY OF HEIDELBERG (DE) | 2020-02-27 | — | — | US | claimed |
| EP-3611256-A1 | APPLICATION OF IMIDAZOPYRIDINE DERIVATIVES IN REGENERATIVE MEDICINE | Universität Heidelberg (DE) | 2020-02-19 | — | — | EP | claimed |
| CN-116970965-A | Electrochemical incomplete hydrogenation method of imidazopyridine compound | 上海兆维科技发展有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-112538087-B | Synthesis method of imidazopyridine compound | 温州大学新材料与产业技术研究院 | 2021-10-15 | — | — | CN | disclosed |
| CN-109438444-B | Imidazo [1, 2-alpha ] pyridine derivative, preparation method and application thereof in allochroic powder | 上海甘田光学材料有限公司 | 2021-03-19 | — | — | CN | disclosed |
| US-20200062719-A1 | Application of Imidazopyridine Derivatives in Regenerative Medicine | UNIVERSITY OF HEIDELBERG (DE) | 2020-02-27 | — | — | US | disclosed |
| US-20200062719-A1 | Application of Imidazopyridine Derivatives in Regenerative Medicine | UNIVERSITY OF HEIDELBERG (DE) | 2020-02-27 | — | — | US | disclosed |
| EP-3611256-A1 | APPLICATION OF IMIDAZOPYRIDINE DERIVATIVES IN REGENERATIVE MEDICINE | Universität Heidelberg (DE) | 2020-02-19 | — | — | EP | disclosed |
| EP-3611256-A1 | APPLICATION OF IMIDAZOPYRIDINE DERIVATIVES IN REGENERATIVE MEDICINE | Universität Heidelberg (DE) | 2020-02-19 | — | — | EP | disclosed |
| US-9590266-B2 | Electrolyte for lithium secondary battery and lithium secondary battery including the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2017-03-07 | — | — | US | disclosed |
| US-9590266-B2 | Electrolyte for lithium secondary battery and lithium secondary battery including the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2017-03-07 | — | — | US | disclosed |
| US-20140206662-A1 | Imidazopyridine Compounds | PROXIMAGEN LTD. (GB) | 2014-07-24 | — | — | US | disclosed |
| CN-103012400-A | Novel synthesis method of pyridino-imidazole compound | UNIV SOOCHOW | 2013-04-03 | — | — | CN | disclosed |
| US-20130078533-A1 | ELECTROLYTE FOR LITHIUM SECONDARY BATTERY AND LITHIUM SECONDARY BATTERY INCLUDING THE SAME | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2013-03-28 | — | — | US | disclosed |
| US-20130078533-A1 | ELECTROLYTE FOR LITHIUM SECONDARY BATTERY AND LITHIUM SECONDARY BATTERY INCLUDING THE SAME | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2013-03-28 | — | — | US | disclosed |
| EP-2573853-A1 | Electrolyte for lithium secondary battery and lithium secondary battery including the same | Samsung Electronics Co., Ltd. (KR) | 2013-03-27 | — | — | EP | disclosed |
| EP-2376490-B1 | IMIDAZOPYRIDINE COMPOUNDS | PROXIMAGEN LTD (GB) | 2013-01-23 | — | — | EP | disclosed |
| US-20120010188-A1 | Imidazopyridine Compounds | PROMIMAGEN LTD. (GB) | 2012-01-12 | — | — | US | disclosed |
| EP-2376490-A1 | IMIDAZOPYRIDINE COMPOUNDS | Proximagen Limited (GB) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010064020-A1 | IMIDAZOPYRIDINE COMPOUNDS | PROXIMAGEN LTD. (GB) | 2010-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010188-A1 | Imidazopyridine Compounds | SSB, MIF, IDO1 | SMN1; SMN2 1109/4885TP53 2306/4885NPC1 1153/4885 |
| US-20200062719-A1 | Application of Imidazopyridine Derivatives in Regenerative Medicine | DOT1L, NSD1, KDM3A | SMN1; SMN2 1685/4885TP53 1427/4885NPC1 4209/4885 |
| US-20140206662-A1 | Imidazopyridine Compounds | SSB, NFKBIA, TPMT | SMN1; SMN2 887/4885TP53 1815/4885NPC1 2286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.