Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 18/20 | 0.38 |
| ▸ | PTAFR | P25105 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17118428 | 1.00 | PDK2 (0.38) | PDK2PTAFR | |
| SCHEMBL24203497 | 0.97 | PDK2 (0.40) | PDK2PTAFR | |
| SCHEMBL24203505 | 0.97 | PDK2 (0.40) | PDK2PTAFR | |
| SCHEMBL20998185 | 0.97 | PDK2 (0.38) | PDK2PTAFR | |
| SCHEMBL17118476 | 0.97 | PDK2 (0.38) | PDK2PTAFR | |
| SCHEMBL17118485 | 0.97 | PDK2 (0.38) | PDK2PTAFR | |
| SCHEMBL17118479 | 0.97 | PDK2 (0.38) | PDK2PTAFR | |
| SCHEMBL17118408 | 0.95 | PDK2 (0.44) | PDK2 | |
| SCHEMBL20997947 | 0.95 | PDK2 (0.44) | PDK2 | |
| SCHEMBL17118478 | 0.94 | PDK2 (0.35) | PDK2PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11258018-B2 | Compounds and organic electronic devices | MERCK PATENT GMBH (DE) | 2022-02-22 | — | — | US | disclosed |
| WO-2020108899-A1 | ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2020-06-04 | — | — | WO | disclosed |
| US-20190348605-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-11-14 | — | — | US | disclosed |
| US-20170317285-A1 | Compounds and Organic Electronic Devices | MERCK PATENT GMBH (DE) | 2017-11-02 | — | — | US | disclosed |
| US-20170317285-A1 | Compounds and Organic Electronic Devices | MERCK PATENT GMBH (DE) | 2017-11-02 | — | — | US | disclosed |
| US-9768391-B2 | Derivatives of 2-diarylaminofluorene and organic electronic compounds containing them | MERCK PATENT GMBH (DE) | 2017-09-19 | — | — | US | disclosed |
| US-9768391-B2 | Derivatives of 2-diarylaminofluorene and organic electronic compounds containing them | MERCK PATENT GMBH (DE) | 2017-09-19 | — | — | US | disclosed |
| EP-2875699-B1 | DERIVATES OF 2-DIARYLAMINOFLUOREN AND ORGANIC ELECTRONIC DEVICES COMPRISING THE SAME | MERCK PATENT GMBH (DE) | 2017-02-15 | — | — | EP | disclosed |
| US-20150207075-A1 | DERIVATIVES OF 2-DIARYLAMINOFLUORENE AND ORGANIC ELECTRONIC COMPOUNDS CONTAINING THEM | MERCK PATENT GMBH (DE) | 2015-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150207075-A1 | DERIVATIVES OF 2-DIARYLAMINOFLUORENE AND ORGANIC ELECTRONIC COMPOUNDS CONTAINING THEM | DDT, AFF2, CYP2F1 | PDK2 718/4885PTAFR 3811/4885 |
| US-20190348605-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | ETV6, CYP2C19, AFF2 | PDK2 1406/4885PTAFR 4553/4885 |
| US-20170317285-A1 | Compounds and Organic Electronic Devices | ETV6, CYP2C19, AFF2 | PDK2 1406/4885PTAFR 4553/4885 |
| US-11258018-B2 | Compounds and organic electronic devices | ETV6, CYP2C19, AFF2 | PDK2 1406/4885PTAFR 4553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.