Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34464583 | 0.90 | MEN1 (0.49) | CYP2A6PDK2ESR1ESR2MEN1 | |
| SCHEMBL25026532 | 0.88 | HSP90AA1 (0.46) | CYP2A6PDK2ESR1ESR2MEN1 | |
| SCHEMBL34464558 | 0.88 | CYP2A6 (0.44) | CYP2A6PDK2ESR1ESR2MEN1 | |
| SCHEMBL30851345 | 0.87 | MEN1 (0.53) | CYP2A6ESR1ESR2MEN1KMT2A | |
| SCHEMBL9974968 | 0.87 | MEN1 (0.53) | CYP2A6ESR1ESR2MEN1KMT2A | |
| SCHEMBL34464550 | 0.86 | MEN1 (0.47) | CYP2A6PDK2ESR1ESR2MEN1 | |
| SCHEMBL34464610 | 0.84 | MEN1 (0.46) | CYP2A6PDK2ESR1ESR2MEN1 | |
| SCHEMBL23713858 | 0.83 | CYP2A6 (0.34) | CYP2A6PDK2ESR1ESR2MEN1 | |
| SCHEMBL19797296 | 0.82 | PDK2 (0.53) | CYP2A6PDK2ESR1ESR2MEN1 | |
| SCHEMBL19822248 | 0.82 | PDK2 (0.53) | CYP2A6PDK2ESR1ESR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11258018-B2 | Compounds and organic electronic devices | MERCK PATENT GMBH (DE) | 2022-02-22 | — | — | US | disclosed |
| US-20190348605-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-11-14 | — | — | US | disclosed |
| US-20170317285-A1 | Compounds and Organic Electronic Devices | MERCK PATENT GMBH (DE) | 2017-11-02 | — | — | US | disclosed |
| US-20170317285-A1 | Compounds and Organic Electronic Devices | MERCK PATENT GMBH (DE) | 2017-11-02 | — | — | US | disclosed |
| US-9768391-B2 | Derivatives of 2-diarylaminofluorene and organic electronic compounds containing them | MERCK PATENT GMBH (DE) | 2017-09-19 | — | — | US | disclosed |
| US-9768391-B2 | Derivatives of 2-diarylaminofluorene and organic electronic compounds containing them | MERCK PATENT GMBH (DE) | 2017-09-19 | — | — | US | disclosed |
| EP-2875699-B1 | DERIVATES OF 2-DIARYLAMINOFLUOREN AND ORGANIC ELECTRONIC DEVICES COMPRISING THE SAME | MERCK PATENT GMBH (DE) | 2017-02-15 | — | — | EP | disclosed |
| US-20150207075-A1 | DERIVATIVES OF 2-DIARYLAMINOFLUORENE AND ORGANIC ELECTRONIC COMPOUNDS CONTAINING THEM | MERCK PATENT GMBH (DE) | 2015-07-23 | — | — | US | disclosed |
| US-20150207075-A1 | DERIVATIVES OF 2-DIARYLAMINOFLUORENE AND ORGANIC ELECTRONIC COMPOUNDS CONTAINING THEM | MERCK PATENT GMBH (DE) | 2015-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150207075-A1 | DERIVATIVES OF 2-DIARYLAMINOFLUORENE AND ORGANIC ELECTRONIC COMPOUNDS CONTAINING THEM | DDT, AFF2, CYP2F1 | CYP2A6 95/4885PDK2 718/4885ESR1 121/4885 |
| US-20190348605-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | ETV6, CYP2C19, AFF2 | CYP2A6 127/4885PDK2 1406/4885ESR1 19/4885 |
| US-20170317285-A1 | Compounds and Organic Electronic Devices | ETV6, CYP2C19, AFF2 | CYP2A6 127/4885PDK2 1406/4885ESR1 19/4885 |
| US-11258018-B2 | Compounds and organic electronic devices | ETV6, CYP2C19, AFF2 | CYP2A6 127/4885PDK2 1406/4885ESR1 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.