⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20644930 | 0.97 | DPP4 (0.34) | — | |
| SCHEMBL21834946 | 0.88 | — | — | |
| SCHEMBL422018 | 0.72 | — | — | |
| SCHEMBL1488095 | 0.72 | — | — | |
| SCHEMBL14395107 | 0.72 | — | — | |
| SCHEMBL5608346 | 0.72 | — | — | |
| SCHEMBL1488027 | 0.70 | DPP4 (0.34) | — | |
| SCHEMBL15899113 | 0.70 | DPP4 (0.34) | — | |
| SCHEMBL420711 | 0.70 | DPP4 (0.34) | — | |
| SCHEMBL4441754 | 0.70 | DPP4 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220024854-A1 | SALTS OF DIAMINOACETALS AND DIAMINOKETALS AND THEIR SYNTHESIS, AND THEIR TRANSFORMATIONS TO DIAMINOACETALS AND DIAMINOKETALS | ADITYA BIRLA CHEMICALS (USA) LLC | 2022-01-27 | — | — | US | disclosed |
| US-11124473-B2 | Salts of diaminoacetals and diaminoketals and their synthesis, and their transformations to diaminoacetals and diaminoketals | ADITYA BIRLA CHEMICALS (USA) LLC (US) | 2021-09-21 | — | — | US | disclosed |
| US-20190016667-A1 | SALTS OF DIAMINOACETALS AND DIAMINOKETALS AND THEIR SYNTHESIS, AND THEIR TRANSFORMATIONS TO DIAMINOACETALS AND DIAMINOKETALS | ADITYA BIRLA CHEMICALS (USA), INC. | 2019-01-17 | — | — | US | disclosed |
| US-9771378-B2 | Fused morpholinopyrimidines and methods of use thereof | DENALI THERAPEUTICS, INC. (US) | 2017-09-26 | — | — | US | disclosed |
| US-20170044182-A1 | FUSED MORPHOLINOPYRIMIDINES AND METHODS OF USE THEREOF | FORUM PHARMACEUTICALS INC. | 2017-02-16 | — | — | US | disclosed |
| WO-2015109109-A1 | FUSED MORPHOLINOPYRIMIDINES AND METHODS OF USE THEREOF | FORUM PHARMACEUTICALS INC. (US) | 2015-07-23 | — | — | WO | disclosed |