Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 2/20 | 0.44 |
| ▸ | AURKA | O14965 | 2/20 | 0.44 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.44 |
| ▸ | GSK3A | P49840 | 2/20 | 0.44 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.44 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.44 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 7/20 | 0.39 |
| ▸ | RAB9A | P51151 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24427867 | 0.80 | ELANE (0.39) | TAOK1CLK4NPC1RAB9AKMT2A | |
| SCHEMBL16228613 | 0.79 | CHEK1 (0.42) | CHEK1AURKADAPK3GSK3ALIMK1 | |
| SCHEMBL15265938 | 0.78 | CHEK1 (0.41) | CHEK1AURKADAPK3GSK3ALIMK1 | |
| SCHEMBL5410344 | 0.78 | CHEK1 (0.41) | CHEK1AURKADAPK3GSK3ALIMK1 | |
| SCHEMBL190246 | 0.78 | NPC1 (0.52) | CHEK1AURKADAPK3GSK3ALIMK1 | |
| SCHEMBL14995449 | 0.77 | CHEK1 (0.39) | CHEK1AURKADAPK3GSK3ALIMK1 | |
| SCHEMBL4120013 | 0.77 | CHEK1 (0.40) | CHEK1AURKADAPK3GSK3ALIMK1 | |
| SCHEMBL4526748 | 0.75 | HTT (0.34) | KMT2AMEN1HTTSMN1; SMN2CDK2 | |
| SCHEMBL16227960 | 0.74 | CHEK1 (0.36) | CHEK1AURKADAPK3GSK3ALIMK1 | |
| SCHEMBL25366934 | 0.73 | CHEK1 (0.42) | CHEK1AURKADAPK3GSK3ALIMK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4638421-A1 | PROCESS TO MAKE GLP1 RA AND INTERMEDIATES THEREFOR | Eli Lilly and Company (US) | 2025-10-29 | — | — | EP | disclosed |
| US-12365682-B2 | Process to make GLP1 RA and intermediates therefor | ELI LILLY AND COMPANY (US) | 2025-07-22 | — | — | US | disclosed |
| US-20250042899-A1 | PROCESS TO MAKE GLP1 RA AND INTERMEDIATES THEREFOR | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2025-02-06 | — | — | US | disclosed |
| WO-2024137426-A1 | PROCESS TO MAKE GLP1 RA AND INTERMEDIATES THEREFOR | ELI LILLY AND COMPANY (US) | 2024-06-27 | — | — | WO | disclosed |
| US-8796256-B2 | Substituted thiazolidinedione indazoles, indoles and benzotriazoles as estrogen-related receptor-α modulators | JANSSEN PHARMACEUTICA NV (BE) | 2014-08-05 | — | — | US | disclosed |
| WO-2011149841-A1 | SUBSTITUTED THIAZOLIDINEDIONE INDAZOLES, INDOLES AND BENZOTRIAZOLES AS ESTROGEN-RELATED RECEPTOR-α MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-12-01 | — | — | WO | disclosed |
| US-20110294780-A1 | SUBSTITUTED THIAZOLIDINEDIONE INDAZOLES, INDOLES AND BENZOTRIAZOLES AS ESTROGEN-RELATED RECEPTOR-a MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12365682-B2 | Process to make GLP1 RA and intermediates therefor | GLP1R, GIPR, NPY4R | CHEK1 4851/4885AURKA 4042/4885DAPK3 900/4885 |
| US-20110294780-A1 | SUBSTITUTED THIAZOLIDINEDIONE INDAZOLES, INDOLES AND BENZOTRIAZOLES AS ESTROGEN-RELATED RECEPTOR-a MODULATORS | ESR2, IGF1R, ESRRA | CHEK1 2272/4885AURKA 4365/4885DAPK3 3235/4885 |
| US-20250042899-A1 | PROCESS TO MAKE GLP1 RA AND INTERMEDIATES THEREFOR | GLP1R, GIPR, NPY4R | CHEK1 4851/4885AURKA 4042/4885DAPK3 900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.