Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 20/20 | 0.67 |
| ▸ | EZH1 | Q92800 | 3/20 | 0.65 |
| ▸ | EED | O75530 | 1/20 | 0.57 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.57 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.57 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16935243 | 0.95 | EZH2 (0.69) | EZH2EZH1EEDRBBP4SUZ12 | |
| SCHEMBL16935218 | 0.86 | EZH2 (0.77) | EZH2EZH1EEDRBBP4SUZ12 | |
| SCHEMBL16935200 | 0.85 | EZH2 (0.69) | EZH2EZH1EEDRBBP4SUZ12 | |
| SCHEMBL16935206 | 0.85 | EZH2 (0.69) | EZH2EZH1EEDRBBP4SUZ12 | |
| SCHEMBL16935356 | 0.84 | EZH2 (0.67) | EZH2EZH1EEDRBBP4SUZ12 | |
| SCHEMBL16935244 | 0.84 | EZH2 (0.68) | EZH2EZH1EEDRBBP4SUZ12 | |
| SCHEMBL16935219 | 0.82 | EZH2 (0.78) | EZH2EZH1 | |
| SCHEMBL16935171 | 0.81 | EZH2 (0.73) | EZH2EZH1 | |
| SCHEMBL16935234 | 0.81 | EZH2 (0.91) | EZH2EZH1EEDRBBP4SUZ12 | |
| SCHEMBL16935355 | 0.81 | EZH2 (0.80) | EZH2EZH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015110999-A1 | EZH2 INHIBITORS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2015-07-30 | — | — | WO | disclosed |