Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 18/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16935400 | 0.94 | EZH2 (0.69) | EZH2HDAC1HDAC6 | |
| SCHEMBL16935205 | 0.92 | EZH2 (0.60) | EZH2HDAC1HDAC6 | |
| SCHEMBL16935294 | 0.91 | EZH2 (0.61) | EZH2HDAC1HDAC6 | |
| SCHEMBL17136164 | 0.90 | EZH2 (0.65) | EZH2HDAC1HDAC6 | |
| SCHEMBL17136167 | 0.90 | EZH2 (0.65) | EZH2HDAC1HDAC6 | |
| SCHEMBL30688045 | 0.89 | EZH2 (0.56) | EZH2HDAC1HDAC6 | |
| SCHEMBL16398434 | 0.89 | EZH2 (0.56) | EZH2HDAC1HDAC6 | |
| SCHEMBL13281854 | 0.86 | EZH2 (0.68) | EZH2HDAC1HDAC6 | |
| Formic Acid SCHEMBL13276938 | 0.86 | EZH2 (0.54) | EZH2HDAC1HDAC6 | |
| SCHEMBL28533361 | 0.86 | EZH2 (0.68) | EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015110999-A1 | EZH2 INHIBITORS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2015-07-30 | — | — | WO | disclosed |