Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C2B | O00750 | 20/20 | 0.74 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.55 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.55 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1281210 | 0.89 | PIK3C2B (0.74) | PIK3C2BPIK3CDPIK3R1PIK3CB | |
| SCHEMBL1281207 | 0.89 | PIK3C2B (0.74) | PIK3C2BPIK3CDPIK3R1PIK3CB | |
| SCHEMBL1281229 | 0.85 | PIK3C2B (1.00) | PIK3C2BPIK3CDPIK3R1PIK3CB | |
| SCHEMBL1281282 | 0.85 | PIK3C2B (1.00) | PIK3C2BPIK3CDPIK3R1PIK3CB | |
| SCHEMBL1282604 | 0.85 | PIK3C2B (0.82) | PIK3C2BPIK3CDPIK3R1PIK3CB | |
| SCHEMBL1281974 | 0.85 | PIK3C2B (0.84) | PIK3C2BPIK3CDPIK3R1PIK3CB | |
| SCHEMBL27921636 | 0.84 | PIK3C2B (0.83) | PIK3C2BPIK3CDPIK3R1PIK3CB | |
| SCHEMBL1281189 | 0.83 | PIK3C2B (0.78) | PIK3C2BPIK3CDPIK3R1PIK3CB | |
| SCHEMBL10193544 | 0.83 | PIK3C2B (0.78) | PIK3C2BPIK3CDPIK3R1PIK3CB | |
| SCHEMBL1281938 | 0.81 | PIK3C2B (0.78) | PIK3C2BPIK3CDPIK3R1PIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047538-A1 | BENZIMIDAZOLE DERIVATIVES AS PI3 KINASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2012-04-12 | — | — | WO | disclosed |