Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | TGM2 | P21980 | 1/20 | 0.31 |
| ▸ | WDR5 | P61964 | 3/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | GALR3 | O60755 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16951336 | 0.82 | TP53 (0.35) | PTGDR2SLC6A4DRD2DRD4DRD3 | |
| SCHEMBL16957289 | 0.81 | KDM4E (0.36) | KDM1AKDM1BKDM4EMEN1MAPT | |
| SCHEMBL16954789 | 0.81 | OPRL1 (0.36) | KRASPTGDRPTGDR2 | |
| SCHEMBL16953955 | 0.81 | OPRL1 (0.36) | — | |
| SCHEMBL16959402 | 0.78 | PTGDR2 (0.36) | MEN1MAPTKMT2APTGDR2TGM2 | |
| SCHEMBL16962251 | 0.77 | NOTUM (0.33) | — | |
| SCHEMBL16955359 | 0.77 | CHRNA1 (0.38) | PTGDR2SLC6A4DRD2DRD3 | |
| SCHEMBL16954717 | 0.75 | POLB (0.37) | KDM4EMAPTPTGDR2TGM2CES2 | |
| SCHEMBL16953200 | 0.75 | PTGDR2 (0.35) | KDM1AKDM1BKDM4EMEN1MAPT | |
| SCHEMBL16951242 | 0.75 | KDM4E (0.38) | KDM4EMAPTKMT2ASLC6A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |