Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.54 |
| ▸ | F2 | P00734 | 4/20 | 0.47 |
| ▸ | F10 | P00742 | 4/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.47 |
| ▸ | F7 | P08709 | 4/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.47 |
| ▸ | F3 | P13726 | 2/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.47 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 3/20 | 0.43 |
| ▸ | ACACA | Q13085 | 2/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | PPIA | P62937 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12073583 | 1.00 | FFAR1 (0.54) | FFAR1F2F10PRSS1F7 | |
| SCHEMBL1696116 | 0.83 | KMT2A (0.53) | F2F10PRSS1F7PRSS2 | |
| SCHEMBL16476684 | 0.83 | KMT2A (0.53) | F2F10PRSS1F7PRSS2 | |
| SCHEMBL1696257 | 0.78 | CHRNA7 (0.46) | FFAR1 | |
| SCHEMBL16476725 | 0.78 | CHRNA7 (0.46) | FFAR1 | |
| SCHEMBL1696259 | 0.78 | CHRNA7 (0.46) | FFAR1 | |
| SCHEMBL1696316 | 0.76 | KMT2A (0.45) | FFAR1F2F10PRSS1F7 | |
| SCHEMBL16476740 | 0.76 | KMT2A (0.45) | FFAR1F2F10PRSS1F7 | |
| SCHEMBL14763055 | 0.74 | FFAR1 (0.63) | FFAR1CXCR2MEN1PABPC1KMT2A | |
| SCHEMBL14763053 | 0.74 | FFAR1 (0.70) | FFAR1CXCR2MEN1PABPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2585457-B1 | Alkaloid aminoester derivatives and medicinal composition thereof | CHIESI FARMA SPA (IT) | 2015-07-22 | — | — | EP | disclosed |
| US-8629160-B2 | Alkaloid aminoester derivatives and medicinal composition thereof | CHIESI FARMACEUTICI S.P.A. (IT) | 2014-01-14 | — | — | US | disclosed |
| EP-2585457-A1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | Chiesi Farmaceutici S.p.A. (IT) | 2013-05-01 | — | — | EP | disclosed |
| WO-2011160918-A1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMACEUTICI S.P.A. (IT) | 2011-12-29 | — | — | WO | disclosed |
| US-20110311461-A1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMACEUTICI S.P.A. (IT) | 2011-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110311461-A1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHRM3, CHRM2, CHRM5 | FFAR1 471/4885F2 4517/4885F10 4807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.