Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 14/20 | 0.39 |
| ▸ | CDK9 | P50750 | 14/20 | 0.39 |
| ▸ | BTK | Q06187 | 6/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13994133 | 0.90 | CCNT1 (0.47) | CCNT1CDK9BTK | |
| SCHEMBL16962620 | 0.90 | BTK (0.40) | CCNT1CDK9BTK | |
| SCHEMBL16961894 | 0.89 | CCNT1 (0.39) | CCNT1CDK9BTK | |
| SCHEMBL16961658 | 0.88 | CCNT1 (0.37) | CCNT1CDK9BTK | |
| SCHEMBL16961891 | 0.87 | CCNT1 (0.42) | CCNT1CDK9 | |
| SCHEMBL5004914 | 0.82 | MKNK1 (0.52) | — | |
| SCHEMBL5010078 | 0.80 | CCNT1 (0.41) | CCNT1CDK9BTK | |
| SCHEMBL13994067 | 0.80 | CCNT1 (0.49) | CCNT1CDK9BTK | |
| SCHEMBL5004818 | 0.79 | CCNT1 (0.49) | CCNT1CDK9BTK | |
| SCHEMBL5010111 | 0.79 | CCNT1 (0.49) | CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900671-A1 | SUBSTITUTED INDAZOL-PYRROLOPYRIMIDINES USEFUL IN THE TREATMENT OF HYPERPROLIFERATIVE DISEASES | Bayer Pharma Aktiengesellschaft (DE) | 2015-08-05 | — | — | EP | claimed |
| EP-2900671-A1 | SUBSTITUTED INDAZOL-PYRROLOPYRIMIDINES USEFUL IN THE TREATMENT OF HYPERPROLIFERATIVE DISEASES | Bayer Pharma Aktiengesellschaft (DE) | 2015-08-05 | — | — | EP | disclosed |