Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.76 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.55 |
| ▸ | CTSG | P08311 | 1/20 | 0.55 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.55 |
| ▸ | CMA1 | P23946 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25970084 | 0.88 | SMN1; SMN2 (0.96) | SMN1; SMN2HPGDNPC1RAB9APRSS1 | |
| SCHEMBL20734830 | 0.87 | SMN1; SMN2 (1.00) | SMN1; SMN2HPGDNPC1RAB9APRSS1 | |
| SCHEMBL18874962 | 0.87 | SMN1; SMN2 (0.61) | SMN1; SMN2HPGDNPC1RAB9APRSS1 | |
| SCHEMBL31746985 | 0.86 | SMN1; SMN2 (0.84) | SMN1; SMN2HPGDNPC1RAB9APRSS1 | |
| SCHEMBL12445445 | 0.84 | SMN1; SMN2 (0.81) | SMN1; SMN2HPGDNPC1RAB9APRSS1 | |
| SCHEMBL30910449 | 0.84 | SMN1; SMN2 (0.87) | SMN1; SMN2HPGDNPC1RAB9APRSS1 | |
| SCHEMBL15577818 | 0.84 | SMN1; SMN2 (0.87) | SMN1; SMN2HPGDNPC1RAB9APRSS1 | |
| SCHEMBL11912071 | 0.84 | SMN1; SMN2 (0.69) | SMN1; SMN2HPGDNPC1RAB9APRSS1 | |
| SCHEMBL10708907 | 0.83 | PRSS1 (0.66) | SMN1; SMN2HPGDNPC1RAB9APRSS1 | |
| SCHEMBL16361209 | 0.83 | SMN1; SMN2 (0.84) | SMN1; SMN2HPGDNPC1RAB9APRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9278146-B2 | Peptide derivative and use of the same | KYOTO UNIVERSITY (JP) | 2016-03-08 | — | — | US | disclosed |
| US-8741291-B2 | Multifunctional antibody conjugates | COVX TECHNOLOGIES IRELAND, LIMITED (IE) | 2014-06-03 | — | — | US | disclosed |
| US-20120087863-A1 | Peptide Derivative and Use of the Same | ARKRAY, INC. (JP) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120087863-A1 | Peptide Derivative and Use of the Same | VIP, IAPP, GLP1R | SMN1; SMN2 4015/4885HPGD 3008/4885NPC1 4600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.