Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 12/20 | 0.43 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexane SCHEMBL16965638 | 0.92 | ALK (0.44) | ALKTNIKPDPK1 | |
| SCHEMBL14377087 | 0.91 | AAK1 (0.42) | ALKTNIK | |
| SCHEMBL14378036 | 0.85 | CLK1 (0.45) | ALKTNIKPDPK1 | |
| SCHEMBL14378193 | 0.83 | AAK1 (0.42) | ALKTNIKPDPK1 | |
| SCHEMBL14378034 | 0.82 | ALK (0.41) | ALKTNIKPDPK1 | |
| SCHEMBL14378029 | 0.81 | ALK (0.41) | ALKTNIKPDPK1 | |
| SCHEMBL15842693 | 0.81 | ALK (0.41) | ALKTNIKPDPK1 | |
| SCHEMBL14378200 | 0.81 | ALK (0.53) | ALKTNIKPDPK1 | |
| SCHEMBL14377085 | 0.81 | ALK (0.56) | ALKTNIKPDPK1 | |
| SCHEMBL14377088 | 0.81 | PDPK1 (0.47) | ALKTNIKPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2723736-B1 | 7-Azaindole derivatives suitable for the treatment of cancers | MERCK PATENT GMBH (DE) | 2015-08-05 | — | — | EP | claimed |
| EP-2723736-B1 | 7-Azaindole derivatives suitable for the treatment of cancers | MERCK PATENT GMBH (DE) | 2015-08-05 | — | — | EP | disclosed |