SCHEMBL16966358

SCHEMBL16966358

CC=Cc1cn2c(-c3ccc(C(=O)NC4CC4)cc3)cnc2c(SC)n1

nearest known ligand 0.73

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TTK P33981 20/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16966356 1.00 TTK (0.73) TTK
SCHEMBL16966384 0.86 TTK (0.70) TTK
SCHEMBL16966382 0.86 TTK (0.70) TTK
SCHEMBL105472 0.85 TTK (0.76) TTK
SCHEMBL104317 0.85 TTK (1.00) TTK
SCHEMBL16966385 0.84 TTK (0.75) TTK
SCHEMBL2371344 0.82 TTK (1.00) TTK
SCHEMBL9936634 0.81 TTK (1.00) TTK
SCHEMBL9936630 0.81 TTK (1.00) TTK
SCHEMBL9936996 0.81 TTK (0.84) TTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2547680-B1 IMIDAZOPYRAZINES BAYER IP GMBH (DE) 2015-08-05 EP claimed
EP-2547680-B1 IMIDAZOPYRAZINES BAYER IP GMBH (DE) 2015-08-05 EP disclosed