Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 19/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16966375 | 0.99 | TTK (0.64) | TTK | |
| SCHEMBL16966353 | 0.97 | TTK (0.65) | TTK | |
| SCHEMBL104265 | 0.95 | TTK (0.70) | TTK | |
| SCHEMBL16966388 | 0.85 | TTK (0.65) | TTK | |
| SCHEMBL16966389 | 0.85 | TTK (0.74) | TTK | |
| SCHEMBL16966381 | 0.84 | TTK (0.52) | TTK | |
| SCHEMBL16966366 | 0.84 | TTK (0.66) | TTK | |
| SCHEMBL16966350 | 0.83 | TTK (0.65) | TTK | |
| SCHEMBL16966359 | 0.82 | TTK (0.67) | TTK | |
| SCHEMBL16966361 | 0.82 | TTK (0.66) | TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2547680-B1 | IMIDAZOPYRAZINES | BAYER IP GMBH (DE) | 2015-08-05 | — | — | EP | claimed |
| EP-2547680-B1 | IMIDAZOPYRAZINES | BAYER IP GMBH (DE) | 2015-08-05 | — | — | EP | disclosed |