Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 20/20 | 0.75 |
| ▸ | AURKB | Q96GD4 | 20/20 | 0.75 |
| ▸ | AURKA | O14965 | 13/20 | 0.75 |
| ▸ | ROCK1 | Q13464 | 9/20 | 0.75 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.75 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.75 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3123947 | 0.91 | PDPK1 (0.79) | PDPK1AURKBAURKAROCK1PIK3CG | |
| SCHEMBL16966462 | 0.91 | PDPK1 (0.79) | PDPK1AURKBAURKAROCK1PIK3CG | |
| SCHEMBL16966452 | 0.91 | PDPK1 (0.79) | PDPK1AURKBAURKAROCK1PIK3CG | |
| SCHEMBL12119541 | 0.89 | PDPK1 (0.85) | PDPK1AURKBAURKAROCK1PIK3CG | |
| SCHEMBL16966483 | 0.86 | PDPK1 (0.68) | PDPK1AURKBAURKAROCK1PIK3CG | |
| SCHEMBL29410282 | 0.86 | PDPK1 (1.00) | PDPK1AURKBAURKAROCK1PIK3CG | |
| SCHEMBL1317022 | 0.86 | PDPK1 (1.00) | PDPK1AURKBAURKAROCK1PIK3CG | |
| SCHEMBL3134306 | 0.84 | PDPK1 (0.66) | PDPK1AURKBAURKAROCK1PIK3CG | |
| SCHEMBL1317753 | 0.84 | PDPK1 (0.67) | PDPK1AURKBAURKAROCK1PIK3CG | |
| SCHEMBL1316853 | 0.84 | PDPK1 (1.00) | PDPK1AURKBAURKAROCK1PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2362775-B1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2015-08-05 | — | — | EP | claimed |
| EP-2362775-B1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2015-08-05 | — | — | EP | disclosed |