⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL169700 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL3293047 | 0.97 | SMN1; SMN2 (0.37) | — | |
| Hydrochloric Acid SCHEMBL5301309 | 0.97 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL19960603 | 0.97 | CXCR4 (0.40) | — | |
| SCHEMBL8581174 | 0.97 | CXCR4 (0.40) | — | |
| SCHEMBL8155578 | 0.97 | POLB (0.37) | — | |
| Ammonia Solution, Strong SCHEMBL175417 | 0.97 | POLB (0.37) | — | |
| Bromide SCHEMBL27980411 | 0.97 | POLB (0.37) | — | |
| Methane SCHEMBL27320849 | 0.97 | MAPT (0.37) | — | |
| SCHEMBL28113997 | 0.93 | MAPT (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1244 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024132278-A1 | SYNTHESIS, PHARMACOLOGY AND USE OF NEW WATER-SOLUBLE AND SELECTIVE FMS-LIKE TYROSINE KINASE 3 (FLT3) INHIBITORS | UNIVERSITÄT REGENSBURG (DE) | 2024-06-27 | — | — | WO | claimed |
| EP-4389223-A1 | SYNTHESIS, PHARMACOLOGY AND USE OF NEW WATER-SOLUBLE AND SELECTIVE FMS-LIKE TYROSINE KINASE 3 (FLT3) INHIBITORS | Universität Regensburg (DE) | 2024-06-26 | — | — | EP | claimed |
| CN-117567392-A | Pterocarpus stilbene paeonol acetic acid compound, and preparation method and medical application thereof | 安徽中医药大学 | 2024-02-20 | — | — | CN | claimed |
| CN-115721649-A | Compound for inhibiting mutant EGFR and application thereof | 华东理工大学 | 2023-03-03 | — | — | CN | claimed |
| US-20220333004-A1 | Dihydroquinoline Photochromic Compounds | TRANSITIONS OPTICAL, LTD. (IE) | 2022-10-20 | — | — | US | claimed |
| CN-110809576-B | FGFR kinase inhibitor and pharmaceutical use | 奥克兰联合服务有限公司 | 2022-08-30 | — | — | CN | claimed |
| EP-4034610-A1 | DIHYDROQUINOLINE PHOTOCHROMIC COMPOUNDS | Transitions Optical, Ltd. (IE) | 2022-08-03 | — | — | EP | claimed |
| CN-114466913-A | Dihydroquinoline photochromic compounds | 光学转变有限公司 | 2022-05-10 | — | — | CN | claimed |
| US-11192890-B2 | FGFR kinase inhibitors and pharmaceutical uses | AUCKLAND UNISERVICES LIMITED (NZ) | 2021-12-07 | — | — | US | claimed |
| US-20210179600-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AS INHIBITORS OF ASK1 | Hepagene Therapeutics (HK) Limited (HK) | 2021-06-17 | — | — | US | claimed |
| EP-0009386-A1 | 2,10-Disubstituted dibenzo(b,d)pyrans and benzo(c)quinolines and pharmaceutical compositions thereof | PFIZER INC. (US) | 1980-04-02 | — | — | EP | claimed |
| EP-0005299-A1 | Substituted 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines, process for the preparation thereof, and pharmaceutical compositions containing them | Technobiotic Ltd. (CH) | 1979-11-14 | — | — | EP | claimed |
| EP-0005380-A2 | Phototropic photosensitive compositions containing a fluoran colorformer | Dynachem Corporation (US) | 1979-11-14 | — | — | EP | claimed |
| EP-0005379-A2 | Photosensitive compositions containing carbonylic halides as activators | Dynachem Corporation (US) | 1979-11-14 | — | — | EP | claimed |
| US-4143139-A | ANALGESICS, HYPOTENSIVES, IMMUNOSUPPRESSANTS, TRANQUILIZERS, ANTISECRETORY, ANTI-ANXIETY | PFIZER INC. (US) | 1979-03-06 | — | — | US | claimed |
| US-4098791-A | Process for preparing 3-(cyanimino)-3-amino-propionitriles | THE UPJOHN COMPANY (US) | 1978-07-04 | — | — | US | claimed |
| US-4067874-A | Novel pyridine 1-oxides | THE UPJOHN COMPANY (US) | 1978-01-10 | — | — | US | claimed |
| US-4026836-A | AMINOMETHACRYLATE SALT CATALYST, REACTING A POLYETHER OR POLYESTER WITH AN AROMATIC POLYISOCYANURATE | TEXACO DEVELOPMENT CORPORATION (US) | 1977-05-31 | — | — | US | claimed |
| US-4009271-A | 6-AZA-3H-1,4-BENZODIAZEPINES | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1977-02-22 | — | — | US | claimed |
| US-4007181-A | ANTIARRHYTHMIA, DIURETIC | THE UPJOHN COMPANY (US) | 1977-02-08 | — | — | US | claimed |