Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.62 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.53 |
| ▸ | PDE4A | P27815 | 3/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.53 |
| ▸ | BCL2 | P10415 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HNF4A | P41235 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM4B | O94953 | 1/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9236954 | 0.87 | BACE1 (0.62) | BACE1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL10338501 | 0.84 | BACE1 (0.52) | BACE1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL1524220 | 0.84 | BACE1 (0.56) | BACE1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL17866726 | 0.83 | PDE4B (0.62) | BACE1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL29884376 | 0.83 | PDE4B (0.62) | BACE1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL16664291 | 0.82 | PDE4B (0.52) | BACE1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL30111104 | 0.82 | BACE1 (0.68) | BACE1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL902287 | 0.82 | BACE1 (0.68) | BACE1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL27558291 | 0.82 | BACE1 (0.56) | BACE1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL21382004 | 0.80 | BACE1 (0.65) | BACE1PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855575-A2 | FLAME RETARDANT POLYCARBONATE COMPOSITIONS, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME | SABIC Innovative Plastics IP B.V. (NL) | 2015-04-08 | — | — | EP | disclosed |
| WO-2013175445-A2 | FLAME RETARDANT POLYCARBONATE COMPOSITIONS, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2013-11-28 | — | — | WO | disclosed |
| EP-2576214-A1 | A MULTILAYER SHEET AND METHODS OF MAKING AND ARTICLES COMPRISING THE MULTILAYER SHEET | SABIC Innovative Plastics IP B.V. (NL) | 2013-04-10 | — | — | EP | disclosed |
| WO-2011148330-A1 | A MULTILAYER SHEET AND METHODS OF MAKING AND ARTICLES COMPRISING THE MULTILAYER SHEET | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2011-12-01 | — | — | WO | disclosed |
| CN-101084181-B | Preparation method of aromatic polycarbonate | ASAHI CHEMICAL IND (JP) | 2011-07-27 | — | — | CN | disclosed |
| CN-101084181-A | Asahi chemical corp (jp) | ASAHI CHEMICAL CORP (JP) | 2007-12-05 | — | — | CN | disclosed |
| US-5206334-A | Improved blow molding characteristics | GENERAL ELECTRIC COMPANY (US) | 1993-04-27 | — | — | US | disclosed |
| US-5105025-A | 2',4,4\"-m-terphenyltriols and fungal strain used to make same | GENERAL ELECTRIC COMPANY (US) | 1992-04-14 | — | — | US | disclosed |
| US-5105025-A | 2',4,4\"-m-terphenyltriols and fungal strain used to make same | GENERAL ELECTRIC COMPANY (US) | 1992-04-14 | — | — | US | disclosed |
| US-5049498-A | Fungal strain used to make 2',4,4\"-m-terphenyltriols | GENERAL ELECTRIC COMPANY (US) | 1991-09-17 | — | — | US | disclosed |
| US-5049498-A | Fungal strain used to make 2',4,4\"-m-terphenyltriols | GENERAL ELECTRIC COMPANY (US) | 1991-09-17 | — | — | US | disclosed |