Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 6/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1515682 | 0.74 | NOTUM (0.36) | NOTUMTSHRHPGDMAPTMEN1 | |
| SCHEMBL17701125 | 0.70 | CYP1A2 (0.48) | NOTUMTSHRALDH1A1SMN1; SMN2ALOX15 | |
| SCHEMBL30225424 | 0.70 | CYP1A2 (0.48) | NOTUMTSHRALDH1A1SMN1; SMN2ALOX15 | |
| SCHEMBL2844835 | 0.68 | NOTUM (0.36) | NOTUMTSHRHPGDMAPTMEN1 | |
| SCHEMBL8970133 | 0.67 | NOTUM (0.37) | NOTUMTSHRHPGDMAPTMEN1 | |
| SCHEMBL30417865 | 0.66 | HPGD (0.45) | NOTUMTSHRHPGDMAPTMEN1 | |
| SCHEMBL9727871 | 0.64 | HPGD (0.46) | NOTUMTSHRHPGDMAPTMEN1 | |
| SCHEMBL5253272 | 0.64 | NOTUM (0.35) | NOTUMTSHRHPGDMAPTMEN1 | |
| SCHEMBL27489322 | 0.64 | NOTUM (0.56) | NOTUMTSHRHPGDMAPTMEN1 | |
| SCHEMBL12401716 | 0.61 | SRD5A2 (0.49) | NOTUMTSHRHPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3099301-A2 | TREATMENTS FOR RESISTANT ACNE | Vyome Biosciences Pvt Ltd (IN) | 2016-12-07 | — | — | EP | disclosed |
| WO-2015114666-A9 | TREATMENTS FOR RESISTANT ACNE | VYOME BIOSCIENCES PVT. LTD. (IN) | 2016-10-20 | — | — | WO | disclosed |
| WO-2015114666-A2 | TREATMENTS FOR RESISTANT ACNE | VYOME BIOSCIENCES PVT. LTD. (IN) | 2015-08-06 | — | — | WO | disclosed |