Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 8/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16975240 | 0.86 | ABL1 (0.36) | ABL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16975259 | 0.85 | ABL1 (0.35) | ABL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16975452 | 0.85 | PIK3CD (0.40) | ABL1PIK3CAPIK3CG | |
| SCHEMBL16975352 | 0.85 | MAPK1 (0.42) | ABL1PIK3CAPIK3CG | |
| SCHEMBL16975261 | 0.84 | ABL1 (0.40) | ABL1PIK3CAPIK3CGNPC1RAB9A | |
| SCHEMBL16975481 | 0.84 | ABL1 (0.40) | ABL1PIK3CAPIK3CGNPC1RAB9A | |
| SCHEMBL16975213 | 0.83 | NPC1 (0.39) | ABL1PIK3CANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16975375 | 0.83 | NPC1 (0.43) | ABL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16975297 | 0.82 | ABL1 (0.40) | ABL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16975372 | 0.82 | NPC1 (0.39) | ABL1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102203-A2 | ANTIBACTERIAL COMBINATIONS COMPRISING POLYMYXIN | SPERO GYRASE, INC. (US) | 2016-12-14 | — | — | EP | disclosed |
| WO-2015114452-A2 | ANTIBACTERIAL COMPOUNDS | BIOTA EUROPE LTD (GB) | 2015-08-06 | — | — | WO | disclosed |